Polyarteritis nodosa epidemiology and demographics: Difference between revisions

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==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Incidence===
===Incidence===
*
*The [[incidence]] of PAN is approximately 3 to 4 per 100,000 individuals worldwide.<ref name="pmid2562798">{{cite journal |vauthors=McMahon BJ, Heyward WL, Templin DW, Clement D, Lanier AP |title=Hepatitis B-associated polyarteritis nodosa in Alaskan Eskimos: clinical and epidemiologic features and long-term follow-up |journal=Hepatology |volume=9 |issue=1 |pages=97–101 |date=January 1989 |pmid=2562798 |doi= |url=}}</ref>
 
===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. ===
===Prevalence===
===Prevalence===
===
*The [[prevalence]] among alaskan population suffering with [[hepatitis B]] infection is approximately 7.7 per 100,000 individuals.
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually. ===
===Case-fatality rate/Mortality rate===
===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
*The case-fatality rate/mortality rate of [disease name] is approximately [number range]. ===
===Age===
===Age===
===
*Patients of all age groups may develop PAN.
*Patients of all age groups may develop [disease name].
*PAN is mostly diagnosed in patients aged 45-65 years. <ref name="pmid16045832">{{cite journal |vauthors=Colmegna I, Maldonado-Cocco JA |title=Polyarteritis nodosa revisited |journal=Curr Rheumatol Rep |volume=7 |issue=4 |pages=288–96 |date=August 2005 |pmid=16045832 |doi= |url=}}</ref>
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group]. ===
===Race===
===Race===
===
*There is no racial predilection to PAN.  
*There is no racial predilection to [disease name].
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name]. ===
===Gender===
===Gender===
===
*Males are more commonly affected by PAN than females. The male to female ratio is approximately 1.5 to 1.
*[Disease name] affects men and women equally.
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1. ===
===Region===
===
*The majority of [disease name] cases are reported in [geographical region].  


*[Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2]. ===
=== Region ===
===Developed Countries===
* Population prevalence estimates for polyarteritis nodosa (PAN) range from 2 to 33 per million across the European Countries <ref name="pmid17553910">{{cite journal| author=Mohammad AJ, Jacobsson LT, Mahr AD, Sturfelt G, Segelmark M| title=Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden. | journal=Rheumatology (Oxford) | year= 2007 | volume= 46 | issue= 8 | pages= 1329-37 | pmid=17553910 | doi=10.1093/rheumatology/kem107 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17553910  }} </ref>  
===Developing Countries===
PAN is a very uncommon disease and a rare form of [[vasculitis]]. Population prevalence estimates for polyarteritis nodosa (PAN) range from 2 to 33 per million across the European Countries <ref name="pmid17553910">{{cite journal| author=Mohammad AJ, Jacobsson LT, Mahr AD, Sturfelt G, Segelmark M| title=Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden. | journal=Rheumatology (Oxford) | year= 2007 | volume= 46 | issue= 8 | pages= 1329-37 | pmid=17553910 | doi=10.1093/rheumatology/kem107 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17553910  }} </ref> and the annual incidence in three regions of Europe was estimated to be 4.4 to 9.7 per million <ref name="pmid10693883">{{cite journal| author=Watts RA, Lane SE, Bentham G, Scott DG| title=Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom. | journal=Arthritis Rheum | year= 2000 | volume= 43 | issue= 2 | pages= 414-9 | pmid=10693883 | doi=10.1002/1529-0131(200002)43:2<414::AID-ANR23>3.0.CO;2-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10693883  }} </ref>.


PAN is commoner in men than women at a predominance rate of 1.5: 1 <ref name="pmid14872461">{{cite journal| author=Mahr A, Guillevin L, Poissonnet M, Aymé S| title=Prevalences of polyarteritis nodosa, microscopic polyangiitis, Wegener's granulomatosis, and Churg-Strauss syndrome in a French urban multiethnic population in 2000: a capture-recapture estimate. | journal=Arthritis Rheum | year= 2004 | volume= 51 | issue= 1 | pages= 92-9 | pmid=14872461 | doi=10.1002/art.20077 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14872461 }} </ref>. It occurs in all ethnic groups. Most cases of PAN occur in the 5th to 6th decade of life. It can also occur in children although this form of presentation is very rare.
* The annual incidence in three regions of Europe was estimated to be 4.4 to 9.7 per million <ref name="pmid10693883">{{cite journal| author=Watts RA, Lane SE, Bentham G, Scott DG| title=Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom. | journal=Arthritis Rheum | year= 2000 | volume= 43 | issue= 2 | pages= 414-9 | pmid=10693883 | doi=10.1002/1529-0131(200002)43:2<414::AID-ANR23>3.0.CO;2-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10693883 }} </ref>.
PAN has been associated with [[hepatitis B virus]] [[infection]].


==References==
==References==

Revision as of 14:06, 11 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3]

Overview

Epidemiology and Demographics

Incidence

  • The incidence of PAN is approximately 3 to 4 per 100,000 individuals worldwide.[1]

Prevalence

  • The prevalence among alaskan population suffering with hepatitis B infection is approximately 7.7 per 100,000 individuals.

Age

  • Patients of all age groups may develop PAN.
  • PAN is mostly diagnosed in patients aged 45-65 years. [2]

Race

  • There is no racial predilection to PAN.

Gender

  • Males are more commonly affected by PAN than females. The male to female ratio is approximately 1.5 to 1.

Region

  • Population prevalence estimates for polyarteritis nodosa (PAN) range from 2 to 33 per million across the European Countries [3]
  • The annual incidence in three regions of Europe was estimated to be 4.4 to 9.7 per million [4].

References

  1. McMahon BJ, Heyward WL, Templin DW, Clement D, Lanier AP (January 1989). "Hepatitis B-associated polyarteritis nodosa in Alaskan Eskimos: clinical and epidemiologic features and long-term follow-up". Hepatology. 9 (1): 97–101. PMID 2562798.
  2. Colmegna I, Maldonado-Cocco JA (August 2005). "Polyarteritis nodosa revisited". Curr Rheumatol Rep. 7 (4): 288–96. PMID 16045832.
  3. Mohammad AJ, Jacobsson LT, Mahr AD, Sturfelt G, Segelmark M (2007). "Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden". Rheumatology (Oxford). 46 (8): 1329–37. doi:10.1093/rheumatology/kem107. PMID 17553910.
  4. Watts RA, Lane SE, Bentham G, Scott DG (2000). "Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom". Arthritis Rheum. 43 (2): 414–9. doi:10.1002/1529-0131(200002)43:2<414::AID-ANR23>3.0.CO;2-0. PMID 10693883.

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