Henoch-Schönlein purpura natural history, complications and prognosis: Difference between revisions

	Henoch-Schönlein purpura Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Henoch-Schönlein purpura from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Henoch-Schönlein purpura natural history, complications and prognosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Henoch-Schönlein purpura natural history, complications and prognosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Henoch-Schönlein purpura natural history, complications and prognosis
CDC on Henoch-Schönlein purpura natural history, complications and prognosis
Henoch-Schönlein purpura natural history, complications and prognosis in the news
Blogs on Henoch-Schönlein purpura natural history, complications and prognosis
Directions to Hospitals Treating Henoch-Schönlein purpura
Risk calculators and risk factors for Henoch-Schönlein purpura natural history, complications and prognosis

VisualWikitext

Revision as of 01:55, 6 February 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural History

Complications

Prognosis

References

Template:WH Template:WS

@@ Line 8: / Line 8: @@
 ==Complications==
 ==Prognosis==
-===Recovery and recurrence===
-Overall prognosis is good in most patients, with one study showing recovery occurring in 94% and 89% of children and adults, respectively (some having needed treatment).<ref name="pmid9153547">{{cite journal |author=Blanco R, Martínez-Taboada VM, Rodríguez-Valverde V, García-Fuentes M, González-Gay MA |title=Henoch-Schönlein purpura in adulthood and childhood: two different expressions of the same syndrome |journal=Arthritis Rheum. |volume=40 |issue=5 |pages=859–64 |year=1997 |pmid=9153547|doi=10.1002/1529-0131(199705)40:5<859::AID-ART12>3.0.CO;2-J}}</ref>
-In children, the condition recurs in about a third of all cases and usually within the first four months after the initial attack. Recurrence is more common in older children and adults.
-===Kidney involvement===
-In adults, kidney involvement progresses to ESRD more often; in a UK series of 37 patients, 10 (27%) progressed to advanced kidney disease; proteinuria, hypertension at presentation, and pathology features (crescentic changes, interstitial fibrosis and tubular atrophy) predicted progression.
-The findings on renal biopsy correlates with the severity of symptoms: asymptomatic hematuria may only have focal mesangial proliferation while those with proteinuria may have marked cellular proliferation or even crescent formation. The number of crescentic glomeruli is an important prognostic factor in determining whether the patient will develop chronic renal disease or end-stage renal disease.
-In end-stage renal disease, some progress to [[hemodialysis]] or equivalent renal replacement therapy (RRT). If a [[kidney transplant]] is found for a patient on RRT, there is a risk of about 35% over 5 years that the disease will recur in the graft (transplanted kidney), and 11% that the graft will fail completely (requiring resumption of the RRT and a further transplant).
 ==References==

Henoch-Schönlein purpura natural history, complications and prognosis: Difference between revisions

Revision as of 01:55, 6 February 2018

Overview

Natural History

Complications

Prognosis

References

Navigation menu