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{{ | '''Ras-related protein Rab-1B''' is a [[protein]] that in humans is encoded by the ''RAB1B'' [[gene]].<ref name="pmid9030196">{{cite journal |vauthors=Chen D, Guo J, Gahl WA | title = RAB GTPases expressed in human melanoma cells | journal = Biochim Biophys Acta | volume = 1355 | issue = 1 | pages = 1–6 |date=March 1997 | pmid = 9030196 | pmc = | doi =10.1016/S0167-4889(96)00169-3 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB1B RAB1B, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81876| accessdate = }}</ref> | ||
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==Interactions== | |||
RAB1B has been shown to [[Protein-protein interaction|interact]] with [[GOLGA2]].<ref name=pmid11306556>{{cite journal |last=Weide |first=T |authorlink= |author2=Bayer M |author3=Köster M |author4=Siebrasse J P |author5=Peters R |author6=Barnekow A |date=April 2001 |title=The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b |journal=EMBO Rep. |volume=2 |issue=4 |pages=336–41 |publisher= |location = England| issn = 1469-221X| pmid = 11306556 |doi = 10.1093/embo-reports/kve065 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1083862 }}</ref> | |||
==References== | ==References== | ||
{{ | {{Reflist}} | ||
==Further reading== | ==Further reading== | ||
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*{{cite journal | *{{cite journal |vauthors=Plutner H, Cox AD, Pind S, etal |title=Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments |journal=J. Cell Biol. |volume=115 |issue= 1 |pages= 31–43 |year= 1991 |pmid= 1918138 |doi=10.1083/jcb.115.1.31 | pmc=2289927 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Soldati T, Rancaño C, Geissler H, Pfeffer SR |title=Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes |journal=J. Biol. Chem. |volume=270 |issue= 43 |pages= 25541–8 |year= 1995 |pmid= 7592724 |doi=10.1074/jbc.270.43.25541 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Wilson AL, Sheridan KM, Erdman RA, Maltese WA |title=Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells |journal=Biochem. J. |volume=318 |issue= Pt 3|pages= 1007–14 |year= 1996 |pmid= 8836150 |doi= 10.1042/bj3181007| pmc=1217717 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Overmeyer JH, Wilson AL, Erdman RA, Maltese WA |title=The Putative "Switch 2" Domain of the Ras-related GTPase, Rab1B, Plays an Essential Role in the Interaction with Rab Escort Protein |journal=Mol. Biol. Cell |volume=9 |issue= 1 |pages= 223–35 |year= 1998 |pmid= 9437002 |doi= 10.1091/mbc.9.1.223| pmc=25245 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Weide T, Koster M, Barnekow A |title=Inactive and active mutants of rab1b are not tightly integrated into target membranes |journal=Int. J. Oncol. |volume=15 |issue= 4 |pages= 727–36 |year= 1999 |pmid= 10493955 |doi= 10.3892/ijo.15.4.727}} | ||
*{{cite journal | | *{{cite journal |vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA Cloning Using In Vitro Site-Specific Recombination |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000 | pmc=310948 }} | ||
*{{cite journal | *{{cite journal |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R | pmc=311072 }} | ||
*{{cite journal | *{{cite journal |vauthors=Simpson JC, Wellenreuther R, Poustka A, etal |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 | pmc=1083732 }} | ||
*{{cite journal | *{{cite journal |vauthors=Weide T, Bayer M, Köster M, etal |title=The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b |journal=EMBO Rep. |volume=2 |issue= 4 |pages= 336–41 |year= 2001 |pmid= 11306556 |doi= 10.1093/embo-reports/kve065 | pmc=1083862 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Zhao H, Ettala O, Väänänen HK |title=Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins |journal=Biochem. Biophys. Res. Commun. |volume=293 |issue= 3 |pages= 1060–5 |year= 2002 |pmid= 12051767 |doi= 10.1016/S0006-291X(02)00326-1 }} | ||
*{{cite journal | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }} | ||
*{{cite journal | *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }} | ||
*{{cite journal | *{{cite journal |vauthors=Wiemann S, Arlt D, Huber W, etal |title=From ORFeome to Biology: A Functional Genomics Pipeline |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 | pmc=528930 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Fischer J, Weide T, Barnekow A |title=The MICAL proteins and rab1: a possible link to the cytoskeleton? |journal=Biochem. Biophys. Res. Commun. |volume=328 |issue= 2 |pages= 415–23 |year= 2005 |pmid= 15694364 |doi= 10.1016/j.bbrc.2004.12.182 }} | ||
*{{cite journal | *{{cite journal |vauthors=Bayer M, Fischer J, Kremerskothen J, etal |title=Identification and characterization of Iporin as a novel interaction partner for rab1 |journal=BMC Cell Biol. |volume=6 |pages= 15 |year= 2006 |pmid= 15796781 |doi= 10.1186/1471-2121-6-15 | pmc=1079803 }} | ||
*{{cite journal | *{{cite journal |vauthors=Mehrle A, Rosenfelder H, Schupp I, etal |title=The LIFEdb database in 2006 |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 | pmc=1347501 }} | ||
*{{cite journal | *{{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Monetta P, Slavin I, Romero N, Alvarez C |title=Rab1b Interacts with GBF1 and Modulates both ARF1 Dynamics and COPI Association |journal=Mol. Biol. Cell |volume=18 |issue= 7 |pages= 2400–10 |year= 2007 |pmid= 17429068 |doi= 10.1091/mbc.E06-11-1005 | pmc=1924811 }} | ||
*{{cite journal |vauthors=Machner MP, Isberg RR |title=A bifunctional bacterial protein links GDI displacement to Rab1 activation |journal=Science |volume=318 |issue= 5852 |pages= 974–7 |year= 2007 |pmid= 17947549 |doi= 10.1126/science.1149121 }} | |||
*{{cite journal | | |||
}} | }} | ||
{{ | {{Refend}} | ||
{{PDB Gallery|geneid=81876}} | |||
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{{ | {{Gene-11-stub}} | ||
Revision as of 08:45, 10 September 2017
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| External IDs | GeneCards: [1] | ||||||
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| Species | Human | Mouse | |||||
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| Location (UCSC) | n/a | n/a | |||||
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Ras-related protein Rab-1B is a protein that in humans is encoded by the RAB1B gene.[1][2]
Interactions
RAB1B has been shown to interact with GOLGA2.[3]
References
- ↑ Chen D, Guo J, Gahl WA (March 1997). "RAB GTPases expressed in human melanoma cells". Biochim Biophys Acta. 1355 (1): 1–6. doi:10.1016/S0167-4889(96)00169-3. PMID 9030196.
- ↑ "Entrez Gene: RAB1B RAB1B, member RAS oncogene family".
- ↑ Weide, T; Bayer M; Köster M; Siebrasse J P; Peters R; Barnekow A (April 2001). "The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b". EMBO Rep. England. 2 (4): 336–41. doi:10.1093/embo-reports/kve065. ISSN 1469-221X. PMC 1083862. PMID 11306556.
Further reading
- Plutner H, Cox AD, Pind S, et al. (1991). "Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments". J. Cell Biol. 115 (1): 31–43. doi:10.1083/jcb.115.1.31. PMC 2289927. PMID 1918138.
- Soldati T, Rancaño C, Geissler H, Pfeffer SR (1995). "Rab7 and Rab9 are recruited onto late endosomes by biochemically distinguishable processes". J. Biol. Chem. 270 (43): 25541–8. doi:10.1074/jbc.270.43.25541. PMID 7592724.
- Wilson AL, Sheridan KM, Erdman RA, Maltese WA (1996). "Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells". Biochem. J. 318 (Pt 3): 1007–14. doi:10.1042/bj3181007. PMC 1217717. PMID 8836150.
- Overmeyer JH, Wilson AL, Erdman RA, Maltese WA (1998). "The Putative "Switch 2" Domain of the Ras-related GTPase, Rab1B, Plays an Essential Role in the Interaction with Rab Escort Protein". Mol. Biol. Cell. 9 (1): 223–35. doi:10.1091/mbc.9.1.223. PMC 25245. PMID 9437002.
- Weide T, Koster M, Barnekow A (1999). "Inactive and active mutants of rab1b are not tightly integrated into target membranes". Int. J. Oncol. 15 (4): 727–36. doi:10.3892/ijo.15.4.727. PMID 10493955.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Weide T, Bayer M, Köster M, et al. (2001). "The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b". EMBO Rep. 2 (4): 336–41. doi:10.1093/embo-reports/kve065. PMC 1083862. PMID 11306556.
- Zhao H, Ettala O, Väänänen HK (2002). "Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins". Biochem. Biophys. Res. Commun. 293 (3): 1060–5. doi:10.1016/S0006-291X(02)00326-1. PMID 12051767.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Fischer J, Weide T, Barnekow A (2005). "The MICAL proteins and rab1: a possible link to the cytoskeleton?". Biochem. Biophys. Res. Commun. 328 (2): 415–23. doi:10.1016/j.bbrc.2004.12.182. PMID 15694364.
- Bayer M, Fischer J, Kremerskothen J, et al. (2006). "Identification and characterization of Iporin as a novel interaction partner for rab1". BMC Cell Biol. 6: 15. doi:10.1186/1471-2121-6-15. PMC 1079803. PMID 15796781.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- Monetta P, Slavin I, Romero N, Alvarez C (2007). "Rab1b Interacts with GBF1 and Modulates both ARF1 Dynamics and COPI Association". Mol. Biol. Cell. 18 (7): 2400–10. doi:10.1091/mbc.E06-11-1005. PMC 1924811. PMID 17429068.
- Machner MP, Isberg RR (2007). "A bifunctional bacterial protein links GDI displacement to Rab1 activation". Science. 318 (5852): 974–7. doi:10.1126/science.1149121. PMID 17947549.
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