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{{Infobox_gene}}
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'''Phosphoglucomutase-2''' is an [[enzyme]] that in humans is encoded by the ''PGM2'' [[gene]].<ref name="pmid9549096">{{cite journal | vauthors = Whitehouse DB, Tomkins J, Lovegrove JU, Hopkinson DA, McMillan WO | title = A phylogenetic approach to the identification of phosphoglucomutase genes | journal = Mol Biol Evol | volume = 15 | issue = 4 | pages = 456–62 |date=May 1998 | pmid = 9549096 | pmc =  | doi =  10.1093/oxfordjournals.molbev.a025942}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PGM2 phosphoglucomutase 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55276| accessdate = }}</ref> PGM2 is a major isozyme in [[red blood cell]]s.
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Phosphoglucomutase 2
| HGNCid = 8906
| Symbol = PGM2
| AltSymbols =; FLJ10983; MSTP006
| OMIM = 172000
| ECnumber = 
| Homologene = 6693
| MGIid = 97564
| Function = {{GNF_GO|id=GO:0000287 |text = magnesium ion binding}} {{GNF_GO|id=GO:0004614 |text = phosphoglucomutase activity}} {{GNF_GO|id=GO:0016853 |text = isomerase activity}}
| Component =  
| Process = {{GNF_GO|id=GO:0005975 |text = carbohydrate metabolic process}} {{GNF_GO|id=GO:0006006 |text = glucose metabolic process}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 55276
    | Hs_Ensembl = ENSG00000169299
    | Hs_RefseqProtein = NP_060760
    | Hs_RefseqmRNA = NM_018290
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 4
    | Hs_GenLoc_start = 37504723
    | Hs_GenLoc_end = 37540953
    | Hs_Uniprot = Q96G03
    | Mm_EntrezGene = 66681
    | Mm_Ensembl = ENSMUSG00000029171
    | Mm_RefseqmRNA = NM_025700
    | Mm_RefseqProtein = NP_079976
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 64372085
    | Mm_GenLoc_end = 64407313
    | Mm_Uniprot = Q7TSV4
  }}
}}
'''Phosphoglucomutase 2''', also known as '''PGM2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PGM2 phosphoglucomutase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55276| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD |title=Regional localization of human phosphoglucomutase-2 locus on chromosome 4. |journal=Exp. Cell Res. |volume=111 |issue= 2 |pages= 492-5 |year= 1978 |pmid= 564278 |doi=  }}
*{{cite journal  | vauthors=Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD |title=Regional localization of human phosphoglucomutase-2 locus on chromosome 4. |journal=Exp. Cell Res. |volume=111 |issue= 2 |pages= 492–5 |year= 1978 |pmid= 564278 |doi=10.1016/0014-4827(78)90200-8 }}
*{{cite journal  | author=Francke U, Brown S |title=Regional assignment of genes for phosphoglucomutase2 and peptidase S to 4pter leads to 4q21 in man. |journal=Cytogenet. Cell Genet. |volume=22 |issue= 1-6 |pages= 401-5 |year= 1979 |pmid= 752511 |doi=  }}
*{{cite journal  | vauthors=Francke U, Brown S |title=Regional assignment of genes for phosphoglucomutase2 and peptidase S to 4pter leads to 4q21 in man. |journal=Cytogenet. Cell Genet. |volume=22 |issue= 1–6 |pages= 401–5 |year= 1979 |pmid= 752511 |doi=10.1159/000130982 }}
*{{cite journal  | author=Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD |title=Human PGM2 (E.C. 2.7.5.1) mapped to 4pter leads to 4q25. |journal=Cytogenet. Cell Genet. |volume=22 |issue= 1-6 |pages= 406-7 |year= 1979 |pmid= 752512 |doi=  }}
*{{cite journal  | vauthors=Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD |title=Human PGM2 (E.C. 2.7.5.1) mapped to 4pter leads to 4q25 |journal=Cytogenet. Cell Genet. |volume=22 |issue= 1–6 |pages= 406–7 |year= 1979 |pmid= 752512 |doi=10.1159/000130983 }}
*{{cite journal  | author=Wijnen LM, Grzeschik KH, Pearson PL, Meera Khan P |title=The human PGM-2 and its chromosomal localization in man-mouse hybrids. |journal=Hum. Genet. |volume=37 |issue= 3 |pages= 271-8 |year= 1977 |pmid= 885546 |doi=  }}
*{{cite journal  | vauthors=Wijnen LM, Grzeschik KH, Pearson PL, Meera Khan P |title=The human PGM-2 and its chromosomal localization in man-mouse hybrids |journal=Hum. Genet. |volume=37 |issue= 3 |pages= 271–8 |year= 1977 |pmid= 885546 |doi=10.1007/BF00393608 }}
*{{cite journal | author=McAlpine PJ, Mohandas T, Komarnicki L, ''et al.'' |title=Further data on the assignment of the phosphoglucomutase2 (PGM2) gene locus to chromosome 4 in man. |journal=Cytogenet. Cell Genet. |volume=14 |issue= 3-6 |pages= 368-9 |year= 1976 |pmid= 1192820 |doi=  }}
*{{cite journal   |vauthors=McAlpine PJ, Mohandas T, Komarnicki L, etal |title=Further data on the assignment of the phosphoglucomutase2 (PGM2) gene locus to chromosome 4 in man |journal=Cytogenet. Cell Genet. |volume=14 |issue= 3–6 |pages= 368–9 |year= 1976 |pmid= 1192820 |doi=10.1159/000130386 }}
*{{cite journal | author=McAlpine PJ, Mohandas T, Komarnicki L, ''et al.'' |title=Further data on the assignment of the phosphoglucomutase (PGM2) gene locus to chromosome 4 in man. |journal=Birth Defects  Orig. Artic. Ser. |volume=11 |issue= 3 |pages= 198-9 |year= 1976 |pmid= 1203483 |doi=  }}
*{{cite journal   |vauthors=McAlpine PJ, Mohandas T, Komarnicki L, etal |title=Further data on the assignment of the phosphoglucomutase (PGM2) gene locus to chromosome 4 in man |journal=Birth Defects  Orig. Artic. Ser. |volume=11 |issue= 3 |pages= 198–9 |year= 1976 |pmid= 1203483 |doi=  }}
*{{cite journal  | author=Hopkinson DA, Harris H |title=Evidence for a second "structural" locus determining human phosphoglucomutase. |journal=Nature |volume=208 |issue= 5008 |pages= 410-2 |year= 1966 |pmid= 5885461 |doi=  }}
*{{cite journal  | vauthors=Hopkinson DA, Harris H |title=Evidence for a second "structural" locus determining human phosphoglucomutase |journal=Nature |volume=208 |issue= 5008 |pages= 410–2 |year= 1966 |pmid= 5885461 |doi=10.1038/208410a0 }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi= }}
*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
*{{cite journal  | author=Whitehouse DB, Tomkins J, Lovegrove JU, ''et al.'' |title=A phylogenetic approach to the identification of phosphoglucomutase genes. |journal=Mol. Biol. Evol. |volume=15 |issue= 4 |pages= 456-62 |year= 1998 |pmid= 9549096 |doi= }}
*{{cite journal   |vauthors=Wiemann S, Weil B, Wellenreuther R, etal |title=Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Gevaert K, Goethals M, Martens L, etal |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
*{{cite journal | author=Gevaert K, Goethals M, Martens L, ''et al.'' |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566-9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Maliekal P, Sokolova T, Vertommen D, etal |title=Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family |journal=J. Biol. Chem. |volume=282 |issue= 44 |pages= 31844–51 |year= 2007 |pmid= 17804405 |doi= 10.1074/jbc.M706818200 }}
*{{cite journal | author=Maliekal P, Sokolova T, Vertommen D, ''et al.'' |title=Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family. |journal=J. Biol. Chem. |volume=282 |issue= 44 |pages= 31844-51 |year= 2007 |pmid= 17804405 |doi= 10.1074/jbc.M706818200 }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 12:12, 24 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Phosphoglucomutase-2 is an enzyme that in humans is encoded by the PGM2 gene.[1][2] PGM2 is a major isozyme in red blood cells.


References

  1. ↑ Whitehouse DB, Tomkins J, Lovegrove JU, Hopkinson DA, McMillan WO (May 1998). "A phylogenetic approach to the identification of phosphoglucomutase genes". Mol Biol Evol. 15 (4): 456–62. doi:10.1093/oxfordjournals.molbev.a025942. PMID 9549096.
  2. ↑ "Entrez Gene: PGM2 phosphoglucomutase 2".

Further reading



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