Liver transplantation historical perspective: Difference between revisions
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* Since the nineties, the field of LT has witnessed a huge expansion of the number of institutions performing the procedure, and today, there are hundreds of liver transplant centres in over 80 countries. | * Since the nineties, the field of LT has witnessed a huge expansion of the number of institutions performing the procedure, and today, there are hundreds of liver transplant centres in over 80 countries. | ||
==References== | ==References== | ||
{ | {Reflists|2} | ||
Revision as of 01:00, 17 December 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
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Liver trasnsplantation Microchapters |
Overview
Liver transplantation historical perspective
- In 1952, Vittorio Staudacher was the first to perform a liver transplantation (LT) in a large animal model, a canine species.[1]
- Two years later, Jack Cannon was credited with the first animal orthotopic LT.[2]
- Thomas Starzl published the first three attempts at human LT, but it was not until 1967 that the procedure resulted in an extended survival.[3]
- Roy Calne, in Cambridge, United Kingdom, joined Roger Williams in London, United Kingdom, in 1968, and reported 5 cases of liver transplant, detailing the technical difficulties encountered
- The introduction of cyclosporine in the late 1970s as part of the immunosuppressive regimen in organ transplantation permitted less toxicity and the prevention of rejection and severe opportunistic infections when compared to azathioprine.[4]
- In 1984, Bismuth reported the first left-lobe LT in a child, and in 1988, Pichlmayr performed the first split-LT in Germany.
- In 1985, Silvano Raia described the first attempt at a living donor graft in a child.[5]
- Since the nineties, the field of LT has witnessed a huge expansion of the number of institutions performing the procedure, and today, there are hundreds of liver transplant centres in over 80 countries.
References
{Reflists|2}
- ↑ Busuttil RW, De Carlis LG, Mihaylov PV, Gridelli B, Fassati LR, Starzl TE (2012). "The first report of orthotopic liver transplantation in the Western world". Am J Transplant. 12 (6): 1385–7. doi:10.1111/j.1600-6143.2012.04026.x. PMID 22458426.
- ↑ Zarrinpar A, Busuttil RW (2013). "Liver transplantation: past, present and future". Nat Rev Gastroenterol Hepatol. 10 (7): 434–40. doi:10.1038/nrgastro.2013.88. PMID 23752825.
- ↑ STARZL TE, MARCHIORO TL, VONKAULLA KN, HERMANN G, BRITTAIN RS, WADDELL WR (1963). "HOMOTRANSPLANTATION OF THE LIVER IN HUMANS". Surg Gynecol Obstet. 117: 659–76. PMC 2634660. PMID 14100514.
- ↑ Calne RY, Rolles K, White DJ, Thiru S, Evans DB, McMaster P; et al. (1979). "Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers". Lancet. 2 (8151): 1033–6. PMID 91781.
- ↑ Strong RW, Lynch SV, Ong TH, Matsunami H, Koido Y, Balderson GA (1990). "Successful liver transplantation from a living donor to her son". N Engl J Med. 322 (21): 1505–7. doi:10.1056/NEJM199005243222106. PMID 2336076.