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==Overview==
==Overview==
===Magnetic Resonance Imaging===
==MRI==
The use of [[Magnetic resonance imaging|MRIs]] as a valuable diagnostic tool in differentiating cardiomyopathy from acute [[myocardial infarction]] and [[myocarditis]] cases.  Cardiac magnetic resonance imaging is helpful in excluding a [[myocardial infarction]] due to the absence of delayed gadolinium hyperenhancement.
The use of [[Magnetic resonance imaging|MRIs]] as a valuable diagnostic tool in differentiating cardiomyopathy from acute [[myocardial infarction]] and [[myocarditis]] cases.  Cardiac magnetic resonance imaging is helpful in excluding a [[myocardial infarction]] due to the absence of delayed gadolinium hyperenhancement.



Revision as of 16:05, 6 January 2017

Stress cardiomyopathy Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Stress Cardiomyopathy from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Unstable angina/non ST elevation myocardial infarction in Stress (Takotsubo) Cardiomyopathy

Future or Investigational Therapies

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

MRI

The use of MRIs as a valuable diagnostic tool in differentiating cardiomyopathy from acute myocardial infarction and myocarditis cases. Cardiac magnetic resonance imaging is helpful in excluding a myocardial infarction due to the absence of delayed gadolinium hyperenhancement.

The Eitel study is the largest (n=256), (multi-center) cardiovascular MRI imaging series of stress cardiomyopathy [1]. Stress cardiomyopathy can be accurately diagnosed by identifying a typical pattern of LV dysfunction, myocardial edema, absence of significant necrosis/fibrosis, and markers of myocardial inflammation. There are four distinct patterns of regional ventricular ballooning: apical (82%), biventricular (34%), midventricular (17%), and basal (1%). Because patients with RV involvement tended to be older, hospitalized for longer, and have markers of heart failure, biventricular ballooning on MRI “may portend a longer and more severe course of disease compared with patients with isolated (LV) involvement.” Dysfunctions in the right ventricle are important to identify due to its effects on morbidity, treatment, and outcome. During follow up MRIs, patients exhibited normalization of LVEF (66%) and inflammatory markers in the absence of significant fibrosis in all patients.

MRI Examples

The MRIs below show a patients heart with apical ballooning and then later after resolution of the apical ballooning.

MRI during apical balllooning: {{#ev:youtube|23w6f71zTXI}} ____

MRI following resolution of apical ballooning: {{#ev:youtube|qE0YrlQ5d1o}}

References

  1. Eitel I, von Knobelsdorff-Brekenhoff F, Bernhardt P, et al. Clinical characteristics and CV magnetic resonance findings in stress (Takotsubo) cardiomyopathy. JAMA 2011; 306:277-286.

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