Germinoma natural history: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
Simrat Sarai (talk | contribs) No edit summary |
||
| Line 14: | Line 14: | ||
==Prognosis== | ==Prognosis== | ||
* Intracranial germinomas have a reported 90% survival to five years after diagnosis.<ref>{{cite journal |author=Packer RJ, Cohen BH, Cooney K, Coney K |title=Intracranial germ cell tumors |journal=Oncologist |volume=5 |issue=4 |pages=312–20 |year=2000 |pmid=10964999 |doi= |url=http://theoncologist.alphamedpress.org/cgi/content/full/5/4/312#R9}}</ref> | *Generally, germinomas are associated with an excellent prognosis. Intracranial germinomas have a reported 90% survival to five years after diagnosis.<ref>{{cite journal |author=Packer RJ, Cohen BH, Cooney K, Coney K |title=Intracranial germ cell tumors |journal=Oncologist |volume=5 |issue=4 |pages=312–20 |year=2000 |pmid=10964999 |doi= |url=http://theoncologist.alphamedpress.org/cgi/content/full/5/4/312#R9}}</ref> | ||
The 10-year survival of germinomas is 70%. | |||
The prognosis of various germ cell tumors is shown below in a tabular form: | |||
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center | |||
|valign=top| | |||
|+ | |||
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Type of tumor}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|5-year survival rate}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | | |||
:Germinoma | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*70-90% | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | |||
:Mixed germ cell tumors | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*60-80% | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | |||
:Nongerminomatous germ cell tumors | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
*30-50% | |||
|- | |||
|} | |||
==References== | ==References== | ||
Revision as of 18:50, 12 February 2016
|
Germinoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Germinoma natural history On the Web |
|
American Roentgen Ray Society Images of Germinoma natural history |
|
Risk calculators and risk factors for Germinoma natural history |
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural history
- Malignant transformation of primordial germ cells that inappropriately migrated during development (either failing to migrate into or out of an area) are the originators of germinomas. There is no histologic differentiation whereas nongerminomatous germ cell tumors display a variety of differentiation.
Complications
Prognosis
- Generally, germinomas are associated with an excellent prognosis. Intracranial germinomas have a reported 90% survival to five years after diagnosis.[1]
The 10-year survival of germinomas is 70%.
The prognosis of various germ cell tumors is shown below in a tabular form:
| Type of tumor | 5-year survival rate |
|---|---|
|
|
|
|
|
|
References
- ↑ Packer RJ, Cohen BH, Cooney K, Coney K (2000). "Intracranial germ cell tumors". Oncologist. 5 (4): 312–20. PMID 10964999.