Williams-Campbell syndrome: Difference between revisions

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==Overview==
'''Williams–Campbell syndrome''' is a [[disease]] of the [[airway]]s where [[cartilage]] in the [[bronchus|bronchi]] is defective. This leads to collapse of the airways and [[bronchiectasis]].<ref name="Palmer">{{cite journal |pages=534–7 |doi=10.1378/chest.113.2.534 |title=Lung Transplantation for Williams-Campbell Syndrome |year=1998 |last1=Palmer |first1=S. M. |last2=Layish |first2=D. T. |last3=Kussin |first3=P. S. |last4=Tapson |first4=V. F. |last5=Oury |first5=T. |last6=Davis |first6=R. D. |journal=Chest |volume=113 |issue=2 |pmid=9498979}}</ref>
'''Williams–Campbell syndrome''' is a [[disease]] of the [[airway]]s where [[cartilage]] in the [[bronchus|bronchi]] is defective. This leads to collapse of the airways and [[bronchiectasis]].<ref name="Palmer">{{cite journal |pages=534–7 |doi=10.1378/chest.113.2.534 |title=Lung Transplantation for Williams-Campbell Syndrome |year=1998 |last1=Palmer |first1=S. M. |last2=Layish |first2=D. T. |last3=Kussin |first3=P. S. |last4=Tapson |first4=V. F. |last5=Oury |first5=T. |last6=Davis |first6=R. D. |journal=Chest |volume=113 |issue=2 |pmid=9498979}}</ref>
Williams–Campbell syndrome is deficiency of the [[bronchial]] [[cartilage]] distally.<ref name="Britishmedical">[[british medical journal]] (BMJ)</ref>
Williams–Campbell syndrome is deficiency of the [[bronchial]] [[cartilage]] distally.<ref name="Britishmedical">[[british medical journal]] (BMJ)</ref>

Revision as of 21:12, 19 January 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Williams–Campbell syndrome is a disease of the airways where cartilage in the bronchi is defective. This leads to collapse of the airways and bronchiectasis.[1] Williams–Campbell syndrome is deficiency of the bronchial cartilage distally.[2]

Symptoms

Diagnosis

Radiologically, the lungs are overinflated and on bronchoscopy bronchomalacia is demonstrated.[2]

History

It was described in 1960 by Howard Williams and Peter Campbell.[3][4]

References

  1. Palmer, S. M.; Layish, D. T.; Kussin, P. S.; Tapson, V. F.; Oury, T.; Davis, R. D. (1998). "Lung Transplantation for Williams-Campbell Syndrome". Chest. 113 (2): 534–7. doi:10.1378/chest.113.2.534. PMID 9498979.
  2. 2.0 2.1 2.2 2.3 2.4 british medical journal (BMJ)
  3. Williams, H; Campbell, P (April 1960). "Generalized Bronchiectasis associated with Deficiency of Cartilage in the Bronchial Tree". Arch. Dis. Child. 35 (180): 182–91. doi:10.1136/adc.35.180.182. PMC 2012546. PMID 13844857.
  4. Jones, VF; Eid, NS; Franco, SM; Badgett, JT; Buchino, JJ (1993). "Familial congenital bronchiectasis: Williams-Campbell syndrome". Pediatric pulmonology. 16 (4): 263–7. doi:10.1002/ppul.1950160410. PMID 8265276.


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