Pseudomyxoma peritonei history and symptoms: Difference between revisions

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* Increased girth
* Increased girth
* [[Infertility]]
* [[Infertility]]
* In advanced disease, increased abdominal girth and complaints of abdominal pain related to intestinal obstruction are the most presenting symptom seen in 30-50% of the PMP patients as a result of disseminated mucinous tumor and ascites classically presenting at laparotomy with jelly belly.  
* In advanced disease, increased abdominal girth and complaints of abdominal pain related to intestinal obstruction are the most presenting symptom seen in 30-50% of the PMP patients as a result of disseminated mucinous tumor and ascites classically presenting at laparotomy with jelly belly.  
* In less advanced disease, local symptoms are seen in 50-80% of PMP patients without jelly belly ascites and might correspond to the site of the primary tumor, such as appendicitis-like symptoms in 25% of cases, or the location of the peritoneal implants, including lower abdominal pain, pelvic pressure and gynecological complaints in females due to the ovarian deposits of the mucinous tumor in 20-30% of the patients.  
* In less advanced disease, local symptoms are seen in 50-80% of PMP patients without jelly belly ascites and might correspond to the site of the primary tumor, such as appendicitis-like symptoms in 25% of cases, or the location of the peritoneal implants, including lower abdominal pain, pelvic pressure and gynecological complaints in females due to the ovarian deposits of the mucinous tumor in 20-30% of the patients.  
* PMP cases presenting with an ulcerated skin fistula on the right flank or a subcutaneous non tender umbilical nodule have also been reported.
* PMP cases presenting with an ulcerated skin fistula on the right flank or a subcutaneous non tender umbilical nodule have also been reported.



Revision as of 14:46, 20 November 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

History

Symptoms

Symptoms of pseudomyxoma peritonei may include:[1][2]

  • Abdominal or pelvic pain
  • Bloating
  • Abdominal distension
  • Digestive disorders
  • Weight changes
  • Increased girth
  • Infertility
  • In advanced disease, increased abdominal girth and complaints of abdominal pain related to intestinal obstruction are the most presenting symptom seen in 30-50% of the PMP patients as a result of disseminated mucinous tumor and ascites classically presenting at laparotomy with jelly belly.
  • In less advanced disease, local symptoms are seen in 50-80% of PMP patients without jelly belly ascites and might correspond to the site of the primary tumor, such as appendicitis-like symptoms in 25% of cases, or the location of the peritoneal implants, including lower abdominal pain, pelvic pressure and gynecological complaints in females due to the ovarian deposits of the mucinous tumor in 20-30% of the patients.
  • PMP cases presenting with an ulcerated skin fistula on the right flank or a subcutaneous non tender umbilical nodule have also been reported.

References

  1. Pseudomyxoma peritonei. Wikipedia. https://en.wikipedia.org/wiki/Pseudomyxoma_peritonei. Accessed on 20 November, 2015.
  2. Amini, Afshin; Masoumi-Moghaddam, Samar; Ehteda, Anahid; Morris, David (2014). "Secreted mucins in pseudomyxoma peritonei: pathophysiological significance and potential therapeutic prospects". Orphanet Journal of Rare Diseases. 9 (1): 71. doi:10.1186/1750-1172-9-71. ISSN 1750-1172.


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