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West Nile fever infection can present with a variety of manifestation according to the severity of the diseases. West Nile fever infection has three different clinical presentations in humans.
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* [[Asymptomatic]] infection
| colspan="1" style="text-align:center; background:LightGreen"|[[EHS ESC guidelines classification scheme#Classification of Recommendations|Class I]]
* Mild [[febrile]] syndrome termed West Nile Fever (febrile stage has an [[incubation period]] of 3-8 days). All symptoms are resolved within 7-10 days, although fatigue can last for some weeks and lymphadenopathy can take up to two months to resolve.<ref>Olejnik E. "Infectious adenitis transmitted by ''Culex molestus''." ''Bull. Res. Counc. Isr.'' 1952; 2:
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210-211.</ref>
| bgcolor="LightGreen"|<nowiki>"</nowiki>'''1.''' xxx. ''([[EHS ESC guidelines classification scheme#Level of Evidence|Level of Evidence: c]])''<nowiki>"</nowiki>
* Neuroinvasive disease termed West Nile [[meningitis]] or [[encephalitis]].<ref>Smithburn K C, Jacobs H R. "Neutralization-tests against neurotropic viruses with sera collected in central Africa." ''Journal of Immunology'' 1942; 44: 923.</ref>
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| bgcolor="LightGreen"|<nowiki>"</nowiki>'''2.''' xxx. ''([[EHS ESC guidelines classification scheme#Level of Evidence|Level of Evidence: A]])''<nowiki>"</nowiki>
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{|class="wikitable"
In infected individuals the ratio between the three states is roughly 110:30:1.<ref>Tsai T F, Popovici F, Cernescu C, Campbell G L, Nedelcu N I. "West Nile encephalitis epidemic in south eastern Romania." ''Lancet'' 1998; 352: 767-771</ref>
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|colspan="1" style="text-align:center; background:LightCoral"|[[EHS ESC guidelines classification scheme#Classification of Recommendations|Class III]]
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|bgcolor="LightCoral"|<nowiki>"</nowiki>'''1.''' xxx. ([[ACC AHA guidelines classification scheme#Level of Evidence|''Level of Evidence: C'']])<nowiki>"</nowiki>
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| colspan="1" style="text-align:center; background:LemonChiffon"|[[EHS ESC guidelines classification scheme#Classification of Recommendations|Class IIa]]
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| bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''1.''' xxx ''([[JNC guidelines classification scheme#Evidence Quality Rating|Level of Evidence: Grade C]])''<nowiki>"</nowiki>
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| bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''2.''' xxx. ''([[EHS ESC guidelines classification scheme#Level of Evidence|Level of Evidence: Grade B]])''<nowiki>"</nowiki>
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| bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''3.''' xxx. ''([[EHS ESC guidelines classification scheme#Level of Evidence|Level of Evidence: Grade C]])''<nowiki>"</nowiki>
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{|class="wikitable"
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| colspan="1" style="text-align:center; background:LemonChiffon"|[[EHS ESC guidelines classification scheme#Classification of Recommendations|Class IIb]]
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| bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''1.''' xxx. ''([[EHS ESC guidelines classification scheme#Level of Evidence|Level of Evidence: Grade C]])''<nowiki>"</nowiki>
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| bgcolor="LemonChiffon"|<nowiki>"</nowiki>'''2.''' xxx. ''([[EHS ESC guidelines classification scheme#Level of Evidence|Level of Evidence: Grade C]])''<nowiki>"</nowiki>
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Revision as of 04:46, 11 September 2014

West Nile fever infection can present with a variety of manifestation according to the severity of the diseases. West Nile fever infection has three different clinical presentations in humans.

  • Asymptomatic infection
  • Mild febrile syndrome termed West Nile Fever (febrile stage has an incubation period of 3-8 days). All symptoms are resolved within 7-10 days, although fatigue can last for some weeks and lymphadenopathy can take up to two months to resolve.[1]
  • Neuroinvasive disease termed West Nile meningitis or encephalitis.[2]

In infected individuals the ratio between the three states is roughly 110:30:1.[3]

  1. ↑ Olejnik E. "Infectious adenitis transmitted by Culex molestus." Bull. Res. Counc. Isr. 1952; 2: 210-211.
  2. ↑ Smithburn K C, Jacobs H R. "Neutralization-tests against neurotropic viruses with sera collected in central Africa." Journal of Immunology 1942; 44: 923.
  3. ↑ Tsai T F, Popovici F, Cernescu C, Campbell G L, Nedelcu N I. "West Nile encephalitis epidemic in south eastern Romania." Lancet 1998; 352: 767-771
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