Granulosa cell tumour: Difference between revisions

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CMG}}
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


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   DiseasesDB    = |
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{{SI}}
{{Granulosa cell tumour}}
{{CMG}}
{{CMG}}


{{EH}}
==[[Granulosa cell tumour overview|Overview]]==


==Overview==
==[[Granulosa cell tumour historical perspective|Historical Perspective]]==
'''Granulosa cell tumours''' (or '''granulosa-theca''') are part of the [[sex cord-stromal tumour]] group of [[Ovarian cancer|ovarian neoplasm]]s.


The peak age at which they occur is 50-55 years, but they may occur at any age.
==[[Granulosa cell tumour pathophysiology|Pathophysiology]]==


==Clinical presentation==
==[[Granulosa cell tumour epidemiology and demographics|Epidemiology & Demographics]]==
[[Estrogen]]s are produced by ''functioning'' tumours, and the clinical presentation depends on the patient's age.
* If the patient is [[postmenopausal]], she usually presents with [[abnormal uterine bleeding]].
* If the patient is of reproductive age, she would present with [[menometrorrhagia]].
* If the patient has not undergone [[puberty]], isosexual-pseudo-precocity may be seen.


==Histology==
==[[Granulosa cell tumour risk factors|Risk Factors]]==
The most characteristic gross appearance is a smooth surfaced solid and cystic lesion with the cysts filled with [[blood]].
 
Hemoperitoneum is an infrequent but classical presentation.
==[[Granulosa cell tumour screening|Screening]]==
A large variety of [[histology|histological]] presentations exists, but they have two key features:
 
#[[Call-Exner bodies]] ([[granulosa cell]]s arranged haphazardly around a space containing [[eosinophilic]] fluid); ''and''
==[[Granulosa cell tumour causes|Causes of Granulosa cell tumour]]==
#Pale uniform nuclei, often with grooves
 
==[[Granulosa cell tumour differential diagnosis|Differentiating Granulosa cell tumour from other Diseases]]==
 
==[[Granulosa cell tumour natural history|Natural History, Complications & Prognosis]]==
 
==Diagnosis==
[[Granulosa cell tumour history and symptoms|History & Symptoms]] | [[Granulosa cell tumour physical examination|Physical Examination]] | [[Granulosa cell tumour laboratory tests|Lab Tests]] | [[Granulosa cell tumour electrocardiogram|Electrocardiogram]] | [[Granulosa cell tumour chest x ray|Chest X Ray]] | [[Granulosa cell tumour CT|CT]] | [[Granulosa cell tumour MRI|MRI]] | [[Granulosa cell tumour echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Granulosa cell tumour other imaging findings|Other Imaging Findings]] | [[Granulosa cell tumour other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Granulosa cell tumour medical therapy|Medical Therapy]] | [[Granulosa cell tumour surgery|Surgery]] | [[Granulosa cell tumour primary prevention|Primary Prevention]] | [[Granulosa cell tumour secondary prevention|Secondary Prevention]] | [[Granulosa cell tumour cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Granulosa cell tumour future or investigational therapies|Future or Investigational Therapies]]


==See also==
==See also==
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{{Epithelial neoplasms}}
{{Epithelial neoplasms}}
{{SIB}}
 
[[Category:Gynecology]]
[[Category:Gynecology]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Mature chapter]]


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Revision as of 22:00, 18 January 2012

For patient information click here

Template:DiseaseDisorder infobox Template:Granulosa cell tumour Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes of Granulosa cell tumour

Differentiating Granulosa cell tumour from other Diseases

Natural History, Complications & Prognosis

Diagnosis

History & Symptoms | Physical Examination | Lab Tests | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

See also

Template:Epithelial neoplasms


Template:WikiDoc Sources

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