Lymphangitis natural history, complications and prognosis: Difference between revisions

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{{Lymphangitis}}
[[Category:Inflammations]]
[[Category:Infectious disease]]
[[Category:Disease]]
{{CMG}}; {{AE}}{{VD}}
{{CMG}}; {{AE}}{{VD}}
==Overview==
==Overview==
Depending on etiologies, lymphangitis has spectrum of natural history, complication, and prognosis. Specific natural history, complications and prognosis for individual infections are discussed in detail separately.
Lymphangitis being a manifestation of wide concurrently occurring spectrum of manifestations or pathologies. Natural history, complications and prognosis varies from etiology to etiology.
== Natural History ==
 
===Acute Lymphangitis===
==Natural History==
*Course of the disease varies from organism to organism.
Lymphangitis being a manifestation of wide concurrently occurring spectrum of manifestations or pathologies. Natural history, complications and prognosis varies from etiology to etiology. In general the
*Generally, if the organism is not locally contained by body defenses, it could lead to bacteremia, sepsis, septic shock, multi-organ failure, and death.
 
===Lymphangitis due to infectious etiology===
Natural history of lymphangitis due to infectious etiology varies widely from organism to organism, but in general, if left untreated or  body defenses weren't able to overcome the pathological nature of organism, could lead to bacteremia, sepsis, septic shock, multi-organ failure, and death.
 
=== Lymphangitis due to non-infectious etiology ===
 
===Lymphangitis carcinomatosa===
===Lymphangitis carcinomatosa===
*An extremely aggressive form metastasized  malignant tumor
Lymphangits carcinomatosis, being a metstatic malignant condition, commonly results in respiratory failure even with treatment.
*In 1996, Bruce DM and colleagues reported, 50% mortality within 3 months of onset of first respiratory symptoms
 
== Complications==
==== Sclerosing lymphangitis ====
===Acute Lymphangitis===
Being a self-limiting and self-resolving condition, If left untreated, it undergoes spontaneous resolvation in weeks.
*Cellulitis  
 
*Pneumonia  
==Complications==
*Endocarditis  
Complications of lymphangitis varies from etiology to etiology.
*Osteomyelitis  
 
*Meningitis  
====Common complications of lymphangitis due to infectious etiology include:====
*Cellulitis
*Pneumonia
*Endocarditis
*Osteomyelitis
*Meningitis
*Septic artheritis
*Septic artheritis
*Peritonitis  
*Peritonitis
*Visceral abscess
*Visceral abscess
*Septic shock
*Septic shock
*Multi-organ failure
*Multi-organ failure
===Lymphangitis carcinomatosa===
 
==== Complications of lymphangits due to non-infectious etiology include: ====
 
====Lymphangitis carcinomatosa====
Most common complications of lymphangitis carcinmatosa are:
*Respiratory failure
*Respiratory failure
*Right Heart failure
*Right Heart failure
== Prognosis ==
==Prognosis==
===Acute Lymphangitis===
Prognosis of lymphangits varies from etiology to etiology
*With appropriate antimicrobial treatment, most attacks of acute lymphangitis resolve within days to weeks.
 
=== Lymphangitis due to infectious etiology ===
With appropriate anitmicrobial treatment, most attacks of lymphangitis with infectious etiology resolve within days to weeks.
 
=== Lymphangitis due to Non-infectious etiology ===
 
===Lymphangitis carcinomatosa===
===Lymphangitis carcinomatosa===
*Being a manifestation of metastatic primary tumor. Lymphangitis carcinomatosa has extremely poor prognosis.  
*Being a manifestation of metastatic primary tumor. Lymphangitis carcinomatosa has extremely poor prognosis with 50% mortality within 3 months of onset of first respiratory symptoms.
 
=== Sclerosing lymphangitis ===
Sclerosing lymphangitis, is self- limiting and self- resolving condition, with excellent prognosis.
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}{{WH}} {{WS}}{{reflist|2}}
{{WH}}
{{WS}}
[[Category:Inflammations]]
[[Category:Infectious disease]]
[[Category:Disease]]
{{reflist|2}}

Revision as of 16:08, 30 December 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vishal Devarkonda, M.B.B.S[2]

Overview

Lymphangitis being a manifestation of wide concurrently occurring spectrum of manifestations or pathologies. Natural history, complications and prognosis varies from etiology to etiology.

Natural History

Lymphangitis being a manifestation of wide concurrently occurring spectrum of manifestations or pathologies. Natural history, complications and prognosis varies from etiology to etiology. In general the

Lymphangitis due to infectious etiology

Natural history of lymphangitis due to infectious etiology varies widely from organism to organism, but in general, if left untreated or body defenses weren't able to overcome the pathological nature of organism, could lead to bacteremia, sepsis, septic shock, multi-organ failure, and death.

Lymphangitis due to non-infectious etiology

Lymphangitis carcinomatosa

Lymphangits carcinomatosis, being a metstatic malignant condition, commonly results in respiratory failure even with treatment.

Sclerosing lymphangitis

Being a self-limiting and self-resolving condition, If left untreated, it undergoes spontaneous resolvation in weeks.

Complications

Complications of lymphangitis varies from etiology to etiology.

Common complications of lymphangitis due to infectious etiology include:

  • Cellulitis
  • Pneumonia
  • Endocarditis
  • Osteomyelitis
  • Meningitis
  • Septic artheritis
  • Peritonitis
  • Visceral abscess
  • Septic shock
  • Multi-organ failure

Complications of lymphangits due to non-infectious etiology include:

Lymphangitis carcinomatosa

Most common complications of lymphangitis carcinmatosa are:

  • Respiratory failure
  • Right Heart failure

Prognosis

Prognosis of lymphangits varies from etiology to etiology

Lymphangitis due to infectious etiology

With appropriate anitmicrobial treatment, most attacks of lymphangitis with infectious etiology resolve within days to weeks.

Lymphangitis due to Non-infectious etiology

Lymphangitis carcinomatosa

  • Being a manifestation of metastatic primary tumor. Lymphangitis carcinomatosa has extremely poor prognosis with 50% mortality within 3 months of onset of first respiratory symptoms.

Sclerosing lymphangitis

Sclerosing lymphangitis, is self- limiting and self- resolving condition, with excellent prognosis.

References

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