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==Treatment of Acute Decompensation of Heart Failure==
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'''Initial stabilization:''' <br>
'''Assess the [[ECG|<span style="color:white;">ECG</span>]]'''<br> ❑ '''Order [[troponin|<span style="color:white;">troponins</span>]]''' <br> ❑ '''Perform a bedside [[echocardiography|<span style="color:white;">echocardiography</span>]] (if available)''' </div>}}
 
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* Oxygen with/without noninvasive ventilation
{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | | | | | | | A00 | | | A00= <div style="float: left; text-align: left; width: 25em; padding:1em;">'''Does the patient fulfill the criteria of [[myocardial infarction|<span style="color:white;">myocardial infarction</span>]]?'''<br><br>
 
❑ Rise and/or fall of [[cardiac biomarker|<span style="color:white;">cardiac biomarker</span>]] (preferably [[troponin|<span style="color:white;">troponin</span>]])<br>
* Sit up and have legs dangling off the bedside
'''''PLUS at least of the following''''' <br>
 
❑ Symptoms of ischemia <br>
* Morphine
❑ New [[ST|<span style="color:white;">ST</span>]]-T wave changes or new [[LBBB|<span style="color:white;">LBBB</span>]] <br>
 
: ''STEMI'' <br>
'''Assess congestion and perfusion:'''<br>
:❑ [[ST elevation|<span style="color:white;">ST elevation</span>]] in at least 2 contiguous leads of 2 mm (0.2 mV) in men or 1.5 mm (0.15 mV) in women in leads V2–V3 and/or of 1 mm (0.1mV) in other contiguous chest leads or the limb leads, '''''OR''''' <br>
 
:❑ [[ST interval#ST Depression|<span style="color:white;">ST depression</span>]] in at least two precordial leads V1-V4 (suggestive of [[posterior MI|<span style="color:white;">posterior MI</span>]]), '''''OR''''' <br>
* Warm and dry (outpatient treatment), OR
:❑ [[ST depression|<span style="color:white;">ST depression</span>]] in several leads plus [[ST elevation|<span style="color:white;">ST elevation</span>]] in lead aVR (suggestive of occlusion of the left main or proximal [[LAD|<span style="color:white;">LAD</span>]] artery)
* Warm and wet (Diuresis +/- vasodilator), OR
: ''NSTEMI''
* Cold and dry (Admission to CCU: with/without inotropes), OR
:❑ [[ST depression|<span style="color:white;">ST depression</span>]] in at least 2 contiguous leads
* Cold and wet (Admission to CCU: diuresis, with/without inotropes)
❑ New [[Q wave|<span style="color:white;">Q wave</span>]] <br>
 
❑ New regional wall abnormality or new myocardial loss </div>}}
'''Admit for in-hospital treatment if:''' <br>
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{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | | | | | A10 | | A11 | A10 = Yes | A11= No}}
 
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'''Identify precipitating factor and treat accordingly:''' <br>
{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | | | | | A12 | | A13 | | A12=<div style="float: left; text-align: left; padding:1em;">Activate cath lab team <br>
* Myocardial infarction
Click here for [[STEMI resident survival guide|<span style="color:white;">STEMI resident survival guide</span>]] <br> Click here for [[NSTEMI resident survival guide|<span style="color:white;">NSTEMI resident survival guide</span>]] </div>| A13=<div style="float: left; text-align: center; padding:1em;">'''Rule out the following life-threatening conditions''' </div>}}
* Myocarditis
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* Renal failure
{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | |,|-|-|-|v|-|-|-|+|-|-|-|-|-|-|-|.| | }}
* Hypertensive crisis
{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | C03 | | C04 | | C05 | | C06 | | C07 | C03= '''[[Pericarditis|<span style="color:white;">Pericarditis</span>]]''' | C04= '''[[Aortic dissection|<span style="color:white;">Aortic dissection</span>]]''' | C05= '''[[Pulmonary embolism|<span style="color:white;">Pulmonary embolism</span>]]'''| C06= '''[[Tension pneumothorax|<span style="color:white;">Tension pneumothorax</span>]]'''| C07= '''[[Esophageal rupture|<span style="color:white;">Esophageal rupture</span>]]'''}}
* Non adherence to medications
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* Worsening aortic stenosis
{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | D03 | | D04 | | D05 | | D06 | | D07| D03=<div style="float: left; text-align: left; width: 12em; padding:1em;">
* Drugs (NSAIDS, thiazides, calcium channel blocker, beta blockers)
'''Look for supportive ECG changes:''' <br> ❑ Diffuse [[ST elevation|<span style="color:white;">ST elevation</span>]], '''''AND/OR'''''<br>
* Toxins (alcohol, anthracyclines)
❑ PR depression, '''''AND/OR''''' <br>
* Arrhythmia
❑ PR elevation in lead aVR 
* COPD
<br>
* PE
'''Look for supportive signs and symptoms:''' <br>
* Anemia
❑ [[Pleuritic pain|<span style="color:white;">Pleuritic pain</span>]] <br>
* Thyroid abnormalities
❑ [[Chest pain|<span style="color:white;">Chest pain</span>]] that is positional <br>
* Systemic infection
❑ [[Viral infection|<span style="color:white;">Viral syndromes</span>]] <br>
 
❑ [[Fever|<span style="color:white;">Fever</span>]] <br>
 
❑ [[Cough|<span style="color:white;">Cough</span>]] <br>
'''Treat congestion and optimize volume status:''' <br>
❑ [[Pericardial rub|<span style="color:white;">Pericardial rub</span>]]</div>
'''''Diuretics''''' <br>
| D04= <div style="float: left; text-align: left; padding:1em;"> '''Look for supportive signs and symptoms:''' <br>
 
❑ Sudden onset of chest pain radiated to the back or interscapular pain<br>
* IV loop diuretics as intermittent boluses or continuous infusion (I-B)
❑ [[Back pain|<span style="color:white;">Back pain</span>]] <br>
* Already on loop diuretics: IV dose >= home PO dose (I-B)
❑ [[Acute heart failure|<span style="color:white;">Acute heart failure</span>]] <br>
* Serial assessment of fluid intake and output, vital signs, body weight (measured every day at the same time) and symptoms
❑ Low pitched early diastolic murmur best heard at the 2nd right intercostal space <br>
* Adjust dose according to volume status (I-B)
❑ Asymmetric blood pressure in the upper extremities <br>
* Daily electrolytes, BUN, creatinine (I-C)
❑ [[Coma|<span style="color:white;">Coma</span>]]<br>
* Persistent symptoms: Increase dose of IV loop diuretics (I-B) OR Add a second diuretics, such as thiazide (I-B)
❑ Diminution or absence of pulse <br>
* Consider low dose dopamine infusion for improved diuresis and renal blood flow (IIb-B)
❑ [[Altered mental status|<span style="color:white;">Altered mental status</span>]] <br>
* Consider renal replacement therapy/Ultrafiltration in obvious volume overload (IIb-B)
❑ Vagal episode <br>
 
❑ Evidence of ischemia <br>
'''''Venodilators'''''<br>
:❑ Splanchnic ischemia <br>
 
:❑ Renal insufficiency <br>
* Consider IV nitroglycerin, nitroprusside, or nesiritide as add-on to diuretics to relieve dyspnea (IIb-A)
:❑ Lower extremity ischemia <br>
 
:❑ Focal neurologic deficits </div>
'''Treat low perfusion:'''<br>
| D05= <div style="float: left; text-align: left; padding:1em;"> '''Look for supportive signs and symptoms:''' <br>
 
❑ [[Pleuritic chest pain|<span style="color:white;">Pleuritic chest pain</span>]]
* Inotropes
❑ [[Dyspnea|<span style="color:white;">Dyspnea</span>]] <br>
 
❑ [[Anxiety|<span style="color:white;">Anxiety</span>]] <br>
'''VTE prevention:'''  
❑ History of:<br>
* Anticoagulation in the absence of contraindications (I-B)
:❑ [[DVT|<span style="color:white;">DVT</span>]]
 
:❑ Recent [[surgery|<span style="color:white;">surgery</span>]]
'''Chronic medical therapy:'''
:❑ [[Malignancy|<span style="color:white;">Malignancy</span>]]
 
:❑ Immobility</div>
* Chronic HFrEF and hemodynamically stable: continue medical therapy
| D06= <div style="float: left; text-align: left; width: 12em; padding:1em;"> '''Look for supportive signs and symptoms:''' <br>
* Initiate beat blockers at a low dose in stable patients following optimization of volume status and D/C IV diuretics and inotropes (I-B)
❑ Sudden [[shortness of breath|<span style="color:white;">Shortness of breath</span>]] <br>
 
❑ [[Cyanosis|<span style="color:white;">Cyanosis</span>]] <br>
'''Management of hyponatremia:'''
❑ [[Penetrating chest wound|<span style="color:white;">Penetrating chest wound</span>]] <br>
 
❑ Flopping sound <br>
* Water restriction
❑ Recent medical procedure <br>
* Optimization of chronic home medications
❑ Patient on [[mechanical ventilation|<span style="color:white;">mechanical ventilation</span>]] <br>
* Persistent hyponatremia and risk of cognitive impairment: vasopressin antagonist for short term (hypervolemic)
❑ Tracheal deviation towards the unaffected side<br>
❑ Absent heart sound on the affected side <br>
❑ Hyperresonance on the affected side </div>
| D07=<div style="float: left; text-align: left; width: 12em; padding:1em;"> '''Look for supportive signs and symptoms:''' <br>
❑ [[Vomiting|<span style="color:white;">Vomiting</span>]] <br>
❑ Lower [[chest pain|<span style="color:white;">chest pain</span>]] <br>
❑ [[Hematemesis|<span style="color:white;">Hematemesis</span>]] <br>
❑ Cervical [[subcutaneous emphysema|<span style="color:white;">subcutaneous emphysema</span>]] <br>
❑ Overindulgence in alcohol <br>
❑ Overindulgence in food </div>}}
{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | |!| | | |!| | | |!| | | |!| | | |!| }}
{{familytree |boxstyle=background: #FA8072; color: #F8F8FF;| | E02 | | E04 | | E05 | | E06 | | E07 | E02= [[Pericarditis resident survival guide|<span style="color:white;">Click here for the detailed management</span>]]| E04= [[Aortic dissection resident survival guide|<span style="color:white;">Click here for the detailed management</span>]]| E05= [[Pulmonary embolism resident survival guide|<span style="color:white;">Click here for the detailed management</span>]]| E06= [[Tension pneumothorax resident survival guide|<span style="color:white;">Click here for the detailed management</span>]]| E07= [[Esophageal rupture resident survival guide|<span style="color:white;">Click here for the detailed management</span>]]}}
{{familytree/end}}

Revision as of 18:42, 12 March 2015

Treatment of Acute Decompensation of Heart Failure

Initial stabilization:

  • Oxygen with/without noninvasive ventilation
  • Sit up and have legs dangling off the bedside
  • Morphine

Assess congestion and perfusion:

  • Warm and dry (outpatient treatment), OR
  • Warm and wet (Diuresis +/- vasodilator), OR
  • Cold and dry (Admission to CCU: with/without inotropes), OR
  • Cold and wet (Admission to CCU: diuresis, with/without inotropes)

Admit for in-hospital treatment if:


Identify precipitating factor and treat accordingly:

  • Myocardial infarction
  • Myocarditis
  • Renal failure
  • Hypertensive crisis
  • Non adherence to medications
  • Worsening aortic stenosis
  • Drugs (NSAIDS, thiazides, calcium channel blocker, beta blockers)
  • Toxins (alcohol, anthracyclines)
  • Arrhythmia
  • COPD
  • PE
  • Anemia
  • Thyroid abnormalities
  • Systemic infection


Treat congestion and optimize volume status:
Diuretics

  • IV loop diuretics as intermittent boluses or continuous infusion (I-B)
  • Already on loop diuretics: IV dose >= home PO dose (I-B)
  • Serial assessment of fluid intake and output, vital signs, body weight (measured every day at the same time) and symptoms
  • Adjust dose according to volume status (I-B)
  • Daily electrolytes, BUN, creatinine (I-C)
  • Persistent symptoms: Increase dose of IV loop diuretics (I-B) OR Add a second diuretics, such as thiazide (I-B)
  • Consider low dose dopamine infusion for improved diuresis and renal blood flow (IIb-B)
  • Consider renal replacement therapy/Ultrafiltration in obvious volume overload (IIb-B)

Venodilators

  • Consider IV nitroglycerin, nitroprusside, or nesiritide as add-on to diuretics to relieve dyspnea (IIb-A)

Treat low perfusion:

  • Inotropes

VTE prevention:

  • Anticoagulation in the absence of contraindications (I-B)

Chronic medical therapy:

  • Chronic HFrEF and hemodynamically stable: continue medical therapy
  • Initiate beat blockers at a low dose in stable patients following optimization of volume status and D/C IV diuretics and inotropes (I-B)

Management of hyponatremia:

  • Water restriction
  • Optimization of chronic home medications
  • Persistent hyponatremia and risk of cognitive impairment: vasopressin antagonist for short term (hypervolemic)