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{{Infobox_gene}}
'''snRNA-activating protein complex subunit 3''' is a [[protein]] that in humans is encoded by the ''SNAPC3'' [[gene]].<ref name="pmid9003788">{{cite journal |author1=Henry RW |author2=Ma B |author3=Sadowski CL |author4=Kobayashi R |author5=Hernandez N | title = Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc | journal = EMBO J | volume = 15 | issue = 24 | pages = 7129–36 |date=February 1997 | pmid = 9003788 | pmc = 452539 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6619| accessdate = }}</ref>
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==Interactions==
SNAPC3 has been shown to [[Protein-protein interaction|interact]] with [[SNAPC1]]<ref name=pmid9003788 /><ref name=pmid11056176>{{cite journal |last=Ma |first=B |authorlink= |author2=Hernandez N  |date=February 2001 |title=A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc |journal=J. Biol. Chem. |volume=276 |issue=7 |pages=5027–35 | issn = 0021-9258| pmid = 11056176 |doi = 10.1074/jbc.M009301200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[Retinoblastoma protein]].<ref name=pmid11094070>{{cite journal |doi=10.1128/MCB.20.24.9182-9191.2000 |last=Hirsch |first=H A |authorlink= |author2=Gu L |author3=Henry R W  |date=Dec 2000 |title=The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression |journal=Mol. Cell. Biol. |volume=20 |issue=24 |pages=9182–91 | issn = 0270-7306| pmid = 11094070 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=102176 }}</ref>
==References==
{{Reflist}}
==Further reading==
{{Refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal  |author1=Bagramian ER |author2=Bogdanova EA |author3=Krymskaia ML |author4=Sokovykh SI |title=[Diagnostic importance of determining 17-ketosteroids in gynecology] |journal=Akusherstvo I Ginekologiia |volume= |issue= 2 |pages= 65–7 |year= 1977 |pmid= 900378 |doi=  }}
*{{cite journal  |author1=Henry RW |author2=Sadowski CL |author3=Kobayashi R |author4=Hernandez N |title=A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. |journal=Nature |volume=374 |issue= 6523 |pages= 653–6 |year= 1995 |pmid= 7715707 |doi= 10.1038/374653a0 |bibcode=1995Natur.374..653H }}
*{{cite journal  |author1=Bai L |author2=Wang Z |author3=Yoon JB |author4=Roeder RG |title=Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III. |journal=Mol. Cell. Biol. |volume=16 |issue= 10 |pages= 5419–26 |year= 1996 |pmid= 8816454 |doi=  | pmc=231541  }}
*{{cite journal  |author1=Ma B |author2=Hernandez N |title=A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. |journal=J. Biol. Chem. |volume=276 |issue= 7 |pages= 5027–35 |year= 2001 |pmid= 11056176 |doi= 10.1074/jbc.M009301200 }}
*{{cite journal  |author1=Hirsch HA |author2=Gu L |author3=Henry RW |title=The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression. |journal=Mol. Cell. Biol. |volume=20 |issue= 24 |pages= 9182–91 |year= 2001 |pmid= 11094070 |doi=10.1128/MCB.20.24.9182-9191.2000  | pmc=102176  }}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M }}
*{{cite journal  |vauthors=Hinkley CS, Hirsch HA, Gu L, etal |title=The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. |journal=J. Biol. Chem. |volume=278 |issue= 20 |pages= 18649–57 |year= 2003 |pmid= 12621023 |doi= 10.1074/jbc.M204247200 }}
*{{cite journal  |vauthors=Humphray SJ, Oliver K, Hunt AR, etal |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465  | pmc=2734081 |bibcode=2004Natur.429..369H }}
*{{cite journal  |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal  |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R }}
*{{cite journal  |vauthors=Jawdekar GW, Hanzlowsky A, Hovde SL, etal |title=The unorthodox SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC. |journal=J. Biol. Chem. |volume=281 |issue= 41 |pages= 31050–60 |year= 2006 |pmid= 16901896 |doi= 10.1074/jbc.M603810200 }}
}}
{{Refend}}
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Small nuclear RNA activating complex, polypeptide 3, 50kDa
| HGNCid = 11136
| Symbol = SNAPC3
| AltSymbols =; MGC132011; MGC33124; PTFbeta; SNAP50
| OMIM = 602348
| ECnumber = 
| Homologene = 31130
| MGIid = 1916338
| GeneAtlas_image1 = PBB_GE_SNAPC3_204001_at_tn.png
| GeneAtlas_image2 = PBB_GE_SNAPC3_210465_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_SNAPC3_222286_at_tn.png
| Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006383 |text = transcription from RNA polymerase III promoter}} {{GNF_GO|id=GO:0009301 |text = snRNA transcription}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6619
    | Hs_Ensembl = ENSG00000164975
    | Hs_RefseqProtein = NP_001034786
    | Hs_RefseqmRNA = NM_001039697
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 9
    | Hs_GenLoc_start = 15412702
    | Hs_GenLoc_end = 15455951
    | Hs_Uniprot = Q92966
    | Mm_EntrezGene = 77634
    | Mm_Ensembl = ENSMUSG00000028483
    | Mm_RefseqmRNA = NM_029949
    | Mm_RefseqProtein = NP_084225
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 82888980
    | Mm_GenLoc_end = 82938828
    | Mm_Uniprot = Q9CQB0
  }}
}}
'''Small nuclear RNA activating complex, polypeptide 3, 50kDa''', also known as '''SNAPC3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6619| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal  | author=Bagramian ER, Bogdanova EA, Krymskaia ML, Sokovykh SI |title=[Diagnostic importance of determining 17-ketosteroids in gynecology] |journal=Akusherstvo i ginekologiia |volume= |issue= 2 |pages= 65-7 |year= 1977 |pmid= 900378 |doi=  }}
*{{cite journal  | author=Henry RW, Sadowski CL, Kobayashi R, Hernandez N |title=A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. |journal=Nature |volume=374 |issue= 6523 |pages= 653-6 |year= 1995 |pmid= 7715707 |doi= 10.1038/374653a0 }}
*{{cite journal  | author=Bai L, Wang Z, Yoon JB, Roeder RG |title=Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III. |journal=Mol. Cell. Biol. |volume=16 |issue= 10 |pages= 5419-26 |year= 1996 |pmid= 8816454 |doi=  }}
*{{cite journal  | author=Henry RW, Ma B, Sadowski CL, ''et al.'' |title=Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc. |journal=EMBO J. |volume=15 |issue= 24 |pages= 7129-36 |year= 1997 |pmid= 9003788 |doi=  }}
*{{cite journal  | author=Ma B, Hernandez N |title=A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. |journal=J. Biol. Chem. |volume=276 |issue= 7 |pages= 5027-35 |year= 2001 |pmid= 11056176 |doi= 10.1074/jbc.M009301200 }}
*{{cite journal  | author=Hirsch HA, Gu L, Henry RW |title=The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression. |journal=Mol. Cell. Biol. |volume=20 |issue= 24 |pages= 9182-91 |year= 2001 |pmid= 11094070 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Hinkley CS, Hirsch HA, Gu L, ''et al.'' |title=The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. |journal=J. Biol. Chem. |volume=278 |issue= 20 |pages= 18649-57 |year= 2003 |pmid= 12621023 |doi= 10.1074/jbc.M204247200 }}
*{{cite journal  | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Jawdekar GW, Hanzlowsky A, Hovde SL, ''et al.'' |title=The unorthodox SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC. |journal=J. Biol. Chem. |volume=281 |issue= 41 |pages= 31050-60 |year= 2006 |pmid= 16901896 |doi= 10.1074/jbc.M603810200 }}
}}
{{refend}}


{{protein-stub}}
{{Gene-9-stub}}
{{WikiDoc Sources}}

Latest revision as of 07:36, 10 January 2019

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

snRNA-activating protein complex subunit 3 is a protein that in humans is encoded by the SNAPC3 gene.[1][2]

Interactions

SNAPC3 has been shown to interact with SNAPC1[1][3] and Retinoblastoma protein.[4]

References

  1. 1.0 1.1 Henry RW; Ma B; Sadowski CL; Kobayashi R; Hernandez N (February 1997). "Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc". EMBO J. 15 (24): 7129–36. PMC 452539. PMID 9003788.
  2. "Entrez Gene: SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa".
  3. Ma, B; Hernandez N (February 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. 276 (7): 5027–35. doi:10.1074/jbc.M009301200. ISSN 0021-9258. PMID 11056176.
  4. Hirsch, H A; Gu L; Henry R W (Dec 2000). "The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression". Mol. Cell. Biol. 20 (24): 9182–91. doi:10.1128/MCB.20.24.9182-9191.2000. ISSN 0270-7306. PMC 102176. PMID 11094070.

Further reading