Methyldopa injection description: Difference between revisions

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#REDIRECT [[Methyldopa#Pharmacology]]
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==DESCRIPTION==
 
Methyldopate HCl Injection, USP, is an antihypertensive agent for intravenous use. Sterile, nonpyrogenic.
 
Methyldopate hydrochloride [levo-3-(3,4-dihydroxyphenyl)-2-methylalanine, ethyl ester hydrochloride] is the ethyl ester of methyldopa, supplied as the hydrochloride salt with a molecular weight of 275.73. Methyldopate hydrochloride is more soluble and stable in solution than methyldopa and is the preferred form for intravenous use.
 
The molecular formula for Methyldopate hydrochloride is C12H17NO4·HCl and the structural formula is:
 
[[image:Methyldopa3.png]]
 
Each mL contains:
 
Methyldopate Hydrochloride ......... 50 mg
 
Citric Acid (Anhydrous) ................. 5 mg
 
Edetate Disodium ......................... 0.5 mg
 
Monothioglycerol ...........................  2 mg
 
Water for Injection ................q.s. to 1 mL
 
Methylparaben 1.5 mg and Propylparaben 0.2 mg added as preservatives, Sodium Bisulfite 3.2 mg added as an antioxidant. pH adjusted with Sodium Hydroxide and/or Hydrochloric Acid.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = METHYLDOPATE HYDROCHLORIDE INJECTION, SOLUTION [AMERICAN REGENT, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f5f25053-a9f3-48b9-a412-078f5ee942fd | publisher =  | date =  | accessdate = 10 March 2014 }}</ref>
 
 
 
 
 
==References==
 
{{Reflist|2}}
 
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]

Latest revision as of 00:13, 22 July 2014