Sandbox AZ1: Difference between revisions

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==Infective Endocarditis Prophylaxis Regimens <ref>Wilson W, et al. Circulation 2007;116;1736-1754.</ref>==
===Oral Surgery===
The target of the infective endocarditis prophylaxis is ''[[Streptococcus viridans]]'':
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! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Able to take Oral Medication}}''
! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Able to take Oral Medication}}''
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen''
! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen''
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''Pediatrics''':'''''[[Amoxicillin]] 50 mg/kg  as a single dose 30-60 min before procedure'''''
| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''Pediatrics''':'''''[[Amoxicillin]] 50 mg/kg  as a single dose 30-60 min before procedure'''''
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{| style="margin: 0 0 0em 0em; border: 1px solid #696969; float: left; width:19em" cellpadding="0" cellspacing="0";
{| style="margin: 0 0 0em 0em; border: 1px solid #696969; float: left; width:19em" cellpadding="0" cellspacing="0";
! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Unable to take Oral Medication}}''
! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Unable to take Oral Medication}}''
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen'
 
! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen''
 
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''Adult''': '''''[[Ampicillin]] 2 g IM or IV as a single dose 30-60 min before procedure '''''
| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''Adult''': '''''[[Ampicillin]] 2 g IM or IV as a single dose 30-60 min before procedure '''''
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''Pediatrics''': '''''[[Ampicillin]] 50 mg/kg as a single dose 30-60 min before procedure'''''
| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''Pediatrics''': '''''[[Ampicillin]] 50 mg/kg as a single dose 30-60 min before procedure'''''
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen''
! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen''
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{| style="margin: 0 0 0em 0em; border: 1px solid #696969; float: left; width:19em" cellpadding="0" cellspacing="0";
{| style="margin: 0 0 0em 0em; border: 1px solid #696969; float: left; width:19em" cellpadding="0" cellspacing="0";
! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Age 1—4 Weeks}}''
! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Age 1—4 Weeks}}''
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen''
! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen''
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Cefotaxime]] 150—200 mg/kg/day IV q6—8h'''''
| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Cefotaxime]] 150—200 mg/kg/day IV q6—8h'''''
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen''
! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen''
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Gentamicin]] 2.5 mg/kg IV q8h''''' <BR> OR <BR>▸'''''[[Tobramycin]] 2.5 mg/kg IV q8h''''' <BR> OR <BR> ▸ '''''[[Amikacin]] 10 mg/kg IV q8h'''''
| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Gentamicin]] 2.5 mg/kg IV q8h''''' <BR> OR <BR>▸'''''[[Tobramycin]] 2.5 mg/kg IV q8h''''' <BR> OR <BR> ▸ '''''[[Amikacin]] 10 mg/kg IV q8h'''''
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{| style="margin: 0 0 0em 0em; border: 1px solid #696969; float: left; width:19em" cellpadding="0" cellspacing="0";
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! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Age 1—23 Months}}''
! style="padding: 0 5px; font-size: 100%; background: #F8F8FF" align=center | ''{{fontcolor|#6C7B8B|Age 1—23 Months}}''
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen''
! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Preferred Regimen''
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| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Cefotaxime]] 150—200 mg/kg/day IV q6—8h'''''
| style="font-size: 80%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Cefotaxime]] 150—200 mg/kg/day IV q6—8h'''''
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! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen''
! style="padding: 0 5px; font-size: 80%; background: #F5F5F5" align=left | ''Alternative Regimen''
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==References==

Latest revision as of 19:35, 14 January 2014

Infective Endocarditis Prophylaxis Regimens [1]

Oral Surgery

The target of the infective endocarditis prophylaxis is Streptococcus viridans:


Able to take Oral Medication
Preferred Regimen
▸ Adult:Amoxicillin 2 gm as a single dose 30-60 min before procedure
▸ Pediatrics:Amoxicillin 50 mg/kg as a single dose 30-60 min before procedure
Unable to take Oral Medication
Preferred Regimen'
▸ Adult: Ampicillin 2 g IM or IV as a single dose 30-60 min before procedure
▸ Pediatrics: Ampicillin 50 mg/kg as a single dose 30-60 min before procedure
Alternative Regimen
▸ Adult: Cefazolin or Ceftriaxone 1 g IM or IV as a single dose 30-60 min before procedure
▸ Pedicatrics:Cefazolin or Ceftriaxone 50 mg/kg IM or IV as a single dose 30-60 min before procedure


Age 1—4 Weeks
Preferred Regimen
▸ Ampicillin 200 mg/kg/day IV q6—8h
AND
▸ Cefotaxime 150—200 mg/kg/day IV q6—8h
Alternative Regimen
▸ Ampicillin 200 mg/kg/day IV q6—8h
AND
▸ Gentamicin 2.5 mg/kg IV q8h
OR
▸Tobramycin 2.5 mg/kg IV q8h
OR
▸ Amikacin 10 mg/kg IV q8h
Age 1—23 Months
Preferred Regimen
▸ Ampicillin 200 mg/kg/day IV q6—8h
AND
▸ Cefotaxime 150—200 mg/kg/day IV q6—8h
Alternative Regimen
▸ Ampicillin 200 mg/kg/day IV q6—8h
AND
▸ Gentamicin 2.5 mg/kg IV q8h
OR
▸Tobramycin 2.5 mg/kg IV q8h
OR
▸ Amikacin 10 mg/kg IV q8h

References
  1. ↑ Wilson W, et al. Circulation 2007;116;1736-1754.
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