Interleukin-28: Difference between revisions

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{{protein
#REDIRECT: [[Interleukin 28]]
| Name = Interleukin 28A
| caption =
| image =
| width =
| HGNCid = 18364
| Symbol = IL28A
| AltSymbols =  , IFNL2
| EntrezGene = 282616
| OMIM = 607401
| RefSeq = NM_172138
| UniProt = Q8IZJ0
| PDB =
| ECnumber =
| Chromosome = 19
| Arm = q
| Band = 13.13
| LocusSupplementaryData =
}}
{{protein
| Name = Interleukin 28B
| caption =
| image =
| width =
| HGNCid = 18365
| Symbol = IL28B
| AltSymbols =  , IFNL3
| EntrezGene = 282617
| OMIM = 607402
| RefSeq = NM_172139
| UniProt = Q8IZI9
| PDB =
| ECnumber =
| Chromosome = 19
| Arm = q
| Band = 13.13
| LocusSupplementaryData =
}}
{{CMG}}
__NOTOC__
 
 
==Overview==
 
'''Interleukin-28''' (IL-28) is a [[cytokine]] that comes in two [[isoform]]s, IL-28A and IL-28B, and plays a role in immune defense against [[virus]]es.<ref>D. Kempuraj et al., Interleukin-28 and 29 (IL-28 and IL-29): new cytokines with anti-viral activities. International Journal of Immunopathology and Pharmacology, 2004, Volume 17, pages 103-106.</ref>  IL-28A and IL-28B belong to the [[type III interferon|type III]] [[interferon]] family of cytokines and are highly similar (in [[amino acid]] sequence) to [[interleukin 29|IL-29]]. 
 
IL-28 [[gene]]s are located near IL-29 on [[chromosome 19]] in humans.
 
==References==
<references/>
 
{{interleukins}}
{{Interferons}}
 
 
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Latest revision as of 19:34, 17 September 2013

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