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{{WBRQuestion
{{WBRQuestion
|QuestionAuthor={{Rim}}
|QuestionAuthor= {{Rim}} (Reviewed by Serge Korjian and  {{YD}})
|ExamType=USMLE Step 1
|ExamType=USMLE Step 1
|MainCategory=Behavioral Science/Psychiatry
|MainCategory=Behavioral Science/Psychiatry
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|MainCategory=Behavioral Science/Psychiatry
|MainCategory=Behavioral Science/Psychiatry
|SubCategory=Dermatology
|SubCategory=Dermatology
|MainCategory=Behavioral Science/Psychiatry
|MainCategory=Behavioral Science/Psychiatry
|MainCategory=Behavioral Science/Psychiatry
|MainCategory=Behavioral Science/Psychiatry
|MainCategory=Behavioral Science/Psychiatry
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|MainCategory=Behavioral Science/Psychiatry
|MainCategory=Behavioral Science/Psychiatry
|SubCategory=Dermatology
|SubCategory=Dermatology
|Prompt=A 5 month old female patient is brought to you by her parents because they are worried she has bruises over her body. Otherwise, they report that they are completely satisfied with the way their daughter is growing. You are worried if the parents are saying the truth and thus you ask that you do a full physical examination of the patient.  Upon examination, you note the following lesions on the patient’s back as shown in the image below. Otherwise, physical examination is unremarkable.  Which of the following is the best next step in your approach towards this patient?
|Prompt=A 6-month-old girl is brought to the pediatrician's office by her parents for concerns over persistent bruising over the lower back. Otherwise, the parents report that the child is developing normally. On physical examination, the physician notes the lesions shown in the image below. Which of the following should be the next step in the management of this patient condition?
 
[[Image:WBR Mongolian Spot.jpg]]
|Explanation=The patient’s physical examination is consistent with [[Mongolian spots]] or [[congenital dermal melanocytosis]]. It is characterized by one or many benign bluish patchy self-limited lesion(s) that is/are very common in infants and typically is/are located at the lower back region, the buttocks, and/or the shoulders.  The condition results from entrapped [[melanocytes]] in the [[dermis]] because of inhibited [[neural crest cell migration]] to the epidermal layer.  Diagnosis is only clinical.  Further work-up in an otherwise healthy child is unnecessary and treatment is not needed because the lesions are self-limited.  The physician should reassure the patient’s family about the benign condition.


Educational Objective:
[[Image:WBR0433.jpg|600px]]
Mongolian spots are benign patchy self-limited lesions that are very common in infants. They are a clinical diagnosis and require no treatment.
|Explanation=The patient’s physical examination is consistent with [[Mongolian spots]] or [[congenital dermal melanocytosis]]. [[Mongolian spots]] are characterized by one or more benign, bluish, patchy, self-limited lesions that are very common among infants and typically are located in the lower back region, the buttocks, and/or the shoulders. The condition results from entrapped [[melanocytes]] in the [[dermis]] due to inhibited [[neural crest cell migration]] to the epidermal layer. Diagnosis of Mongolian spots is clinical. Although these lesions resemble bruising, real bruises usually change color in a short duration and usually appear in different stages of healing. Further work-up in an otherwise healthy child is unnecessary, and treatment is not required given the self-limited nature of the lesions. Therefore, the physician in this vignette should reassure the patient’s family without the need for any further investigation.
|AnswerA=Reassurance
|AnswerA=Reassurance
|AnswerAExp=In the context of a normally growing infant that does not appear to have any abnormality, the physician is only required to reassure the patient’s parents because generally, Mongolian spots disappear by early childhood.
|AnswerAExp=In the context of a normally growing infant, the physician should reassure the parents since [[Mongolian spots]] are self-limited skin lesions that disappear by early childhood.
|AnswerB=Calling the police
|AnswerB=Calling the police
|AnswerBExp=Although child abuse, which requires immediate calling the police, should always be in the differential diagnosis of Mongolian spots, child abuse would not cause such characteristic bluish-lesions despite their resemblance to traumatic bruises. Child abuse can have more symptoms also, such as multiple fractures of different ages, retinal hemorrhages, subdural hematomas, etc… all of which are not present in this child. In the case of child abuse, the infant care may probably be compromised as well and the development of the child may be delayed.
|AnswerBExp=Although [[child abuse]] should always be in the differential diagnosis of Mongolian spots, child abuse would not cause such characteristic bluish-lesions despite their resemblance to traumatic bruises. Children who are victims of abuse may have other findings on physical examination and work-up, such as multiple fractures of different age on skeletal x-ray, [[retinal hemorrhage]]s, and [[subdural hematoma]]s. In the case of child abuse, the infant care is typically compromised as well, and the development of the child may be delayed.
|AnswerC=Performing x-rays
|AnswerC=Performing x-rays
|AnswerCExp=Further testing is not required for patients with Mongolian spots who are otherwise healthy.
|AnswerCExp=Further testing is not required for patients with [[Mongolian spots]] who are otherwise healthy with no suspicion for child abuse.
|AnswerD=Genetic testing
|AnswerD=Genetic testing
|AnswerDExp=Further testing is not required for patients with Mongolian spots who are otherwise healthy.
|AnswerDExp=Further testing is not required for patients with [[Mongolian spots]] who are otherwise healthy.
|AnswerE=Bone marrow biopsy
|AnswerE=Bone marrow biopsy
|AnswerEExp=In the case of a hematologic malignancy that can cause thrombocytopenia and easy bruising, a bone marrow biopsy is indicated; but the child is not expected to be growing with normal development.
|AnswerEExp=A bone marrow biopsy is indicated in the case of a hematologic malignancy that can cause [[thrombocytopenia]] and easy bruising. However, the infant is healthy and is growing well. His presentation is not suspicious for a hematologic malignancy.
|EducationalObjectives=Mongolian spots are benign, patchy, self-limited lesions that are very common among infants. Diagnosis of Mongolian spots is clinical, and no further work-up or investigation is required when Mongolian spots are diagnosed in an otherwise healthy infant.
|References=Cordova A. The Mongolian spot: a study of ethnic differences and a literature review. Clin Pediatr (Phila). 1981;20(11):714-9.<br>
Image attribution: "6 month old Taiwanese baby girl" by user: abby lu for Flickr website (URL: https://www.flickr.com/photos/10620262@N08/924641583/) licensed under Creative Commons attribution 2.0 generic (URL: https://creativecommons.org/licenses/by/2.0/#). No changes were made. Retrieved March 2 2015.<br>
|RightAnswer=A
|RightAnswer=A
|WBRKeyword=Mongolian, spot, abuse, child, police, reassurance
|WBRKeyword=Mongolian spot, Child abuse, Physical examination, Infant, Congenital dermal melanocytosis
|Approved=No
|Approved=No
}}
}}

Latest revision as of 00:32, 28 October 2020

 
Author [[PageAuthor::Rim Halaby, M.D. [1] (Reviewed by Serge Korjian and Yazan Daaboul, M.D.)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Behavioral Science/Psychiatry
Sub Category SubCategory::Dermatology
Prompt [[Prompt::A 6-month-old girl is brought to the pediatrician's office by her parents for concerns over persistent bruising over the lower back. Otherwise, the parents report that the child is developing normally. On physical examination, the physician notes the lesions shown in the image below. Which of the following should be the next step in the management of this patient condition?

]]

Answer A AnswerA::Reassurance
Answer A Explanation [[AnswerAExp::In the context of a normally growing infant, the physician should reassure the parents since Mongolian spots are self-limited skin lesions that disappear by early childhood.]]
Answer B AnswerB::Calling the police
Answer B Explanation [[AnswerBExp::Although child abuse should always be in the differential diagnosis of Mongolian spots, child abuse would not cause such characteristic bluish-lesions despite their resemblance to traumatic bruises. Children who are victims of abuse may have other findings on physical examination and work-up, such as multiple fractures of different age on skeletal x-ray, retinal hemorrhages, and subdural hematomas. In the case of child abuse, the infant care is typically compromised as well, and the development of the child may be delayed.]]
Answer C AnswerC::Performing x-rays
Answer C Explanation [[AnswerCExp::Further testing is not required for patients with Mongolian spots who are otherwise healthy with no suspicion for child abuse.]]
Answer D AnswerD::Genetic testing
Answer D Explanation [[AnswerDExp::Further testing is not required for patients with Mongolian spots who are otherwise healthy.]]
Answer E AnswerE::Bone marrow biopsy
Answer E Explanation [[AnswerEExp::A bone marrow biopsy is indicated in the case of a hematologic malignancy that can cause thrombocytopenia and easy bruising. However, the infant is healthy and is growing well. His presentation is not suspicious for a hematologic malignancy.]]
Right Answer RightAnswer::A
Explanation [[Explanation::The patient’s physical examination is consistent with Mongolian spots or congenital dermal melanocytosis. Mongolian spots are characterized by one or more benign, bluish, patchy, self-limited lesions that are very common among infants and typically are located in the lower back region, the buttocks, and/or the shoulders. The condition results from entrapped melanocytes in the dermis due to inhibited neural crest cell migration to the epidermal layer. Diagnosis of Mongolian spots is clinical. Although these lesions resemble bruising, real bruises usually change color in a short duration and usually appear in different stages of healing. Further work-up in an otherwise healthy child is unnecessary, and treatment is not required given the self-limited nature of the lesions. Therefore, the physician in this vignette should reassure the patient’s family without the need for any further investigation.

Educational Objective: Mongolian spots are benign, patchy, self-limited lesions that are very common among infants. Diagnosis of Mongolian spots is clinical, and no further work-up or investigation is required when Mongolian spots are diagnosed in an otherwise healthy infant.
References: Cordova A. The Mongolian spot: a study of ethnic differences and a literature review. Clin Pediatr (Phila). 1981;20(11):714-9.
Image attribution: "6 month old Taiwanese baby girl" by user: abby lu for Flickr website (URL: https://www.flickr.com/photos/10620262@N08/924641583/) licensed under Creative Commons attribution 2.0 generic (URL: https://creativecommons.org/licenses/by/2.0/#). No changes were made. Retrieved March 2 2015.
]]

Approved Approved::No
Keyword WBRKeyword::Mongolian spot, WBRKeyword::Child abuse, WBRKeyword::Physical examination, WBRKeyword::Infant, WBRKeyword::Congenital dermal melanocytosis
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