SLC7A2: Difference between revisions

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{{Infobox_gene}}
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'''Low affinity [[cationic]] [[amino acid transporter]] 2''' is a [[protein]] that in [[human]]s is encoded by the ''SLC7A2'' [[gene]].<ref name="pmid8954799">{{cite journal | vauthors = Hoshide R, Ikeda Y, Karashima S, Matsuura T, Komaki S, Kishino T, Niikawa N, Endo F, Matsuda I | title = Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2) | journal = Genomics | volume = 38 | issue = 2 | pages = 174–8 |date=Mar 1997 | pmid = 8954799 | pmc =  | doi = 10.1006/geno.1996.0613 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6542| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
| HGNCid = 11060
| Symbol = SLC7A2
| AltSymbols =; ATRC2; CAT-2; HCAT2
| OMIM = 601872
| ECnumber =
| Homologene = 20659
| MGIid = 99828
  | GeneAtlas_image1 = PBB_GE_SLC7A2_207626_s_at_tn.png
| Function = {{GNF_GO|id=GO:0015174 |text = basic amino acid transmembrane transporter activity}}{{GNF_GO|id=GO:0015179 |text = L-amino acid transmembrane transporter activity}}{{GNF_GO|id=GO:0015359 |text = amino acid transmembrane transporter activity}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006520 |text = amino acid metabolic process}} {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0015807 |text = L-amino acid transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6542
    | Hs_Ensembl = ENSG00000003989
    | Hs_RefseqProtein = NP_001008539
    | Hs_RefseqmRNA = NM_001008539
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 8
    | Hs_GenLoc_start = 17440685
    | Hs_GenLoc_end = 17472296
    | Hs_Uniprot = P52569
    | Mm_EntrezGene = 11988
    | Mm_Ensembl = ENSMUSG00000031596
    | Mm_RefseqmRNA = NM_001044740
    | Mm_RefseqProtein = NP_001038205
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 8
    | Mm_GenLoc_start = 42397761
    | Mm_GenLoc_end = 42415357
    | Mm_Uniprot = Q38RA6
  }}
}}
 
 
 
'''Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2''', also known as '''SLC7A2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6542| accessdate = }}</ref>
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{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=González M, Flores C, Pearson JD, ''et al.'' |title=Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells. |journal=Pflugers Arch. |volume=448 |issue= 4 |pages= 383-94 |year= 2005 |pmid= 15064952 |doi= 10.1007/s00424-004-1261-x }}
*{{cite journal   |vauthors=González M, Flores C, Pearson JD, etal |title=Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells. |journal=Pflügers Arch. |volume=448 |issue= 4 |pages= 383–94 |year= 2005 |pmid= 15064952 |doi= 10.1007/s00424-004-1261-x }}
*{{cite journal  | author=Schnorr O, Suschek CV, Kolb-Bachofen V |title=The importance of cationic amino acid transporter expression in human skin. |journal=J. Invest. Dermatol. |volume=120 |issue= 6 |pages= 1016-22 |year= 2003 |pmid= 12787129 |doi= 10.1046/j.1523-1747.2003.12139.x }}
*{{cite journal  | vauthors=Schnorr O, Suschek CV, Kolb-Bachofen V |title=The importance of cationic amino acid transporter expression in human skin. |journal=J. Invest. Dermatol. |volume=120 |issue= 6 |pages= 1016–22 |year= 2003 |pmid= 12787129 |doi= 10.1046/j.1523-1747.2003.12139.x }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal  | author=Hammermann R, Brunn G, Racké K |title=Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4. |journal=Amino Acids |volume=21 |issue= 2 |pages= 211-9 |year= 2002 |pmid= 11665818 |doi=  }}
*{{cite journal  | vauthors=Hammermann R, Brunn G, Racké K |title=Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4. |journal=Amino Acids |volume=21 |issue= 2 |pages= 211–9 |year= 2002 |pmid= 11665818 |doi=10.1007/s007260170029 }}
*{{cite journal | author=Closs EI, Gräf P, Habermeier A, ''et al.'' |title=Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. |journal=Biochemistry |volume=36 |issue= 21 |pages= 6462-8 |year= 1997 |pmid= 9174363 |doi= 10.1021/bi962829p }}
*{{cite journal   |vauthors=Closs EI, Gräf P, Habermeier A, etal |title=Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. |journal=Biochemistry |volume=36 |issue= 21 |pages= 6462–8 |year= 1997 |pmid= 9174363 |doi= 10.1021/bi962829p }}
*{{cite journal  | author=Hoshide R, Ikeda Y, Karashima S, ''et al.'' |title=Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2). |journal=Genomics |volume=38 |issue= 2 |pages= 174-8 |year= 1997 |pmid= 8954799 |doi= 10.1006/geno.1996.0613 }}
}}
}}
{{refend}}
{{refend}}


{{NLM content}}
{{NLM content}}
{{Membrane transport proteins}}
{{Membrane transport proteins}}
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[[Category:Solute carrier family]]
[[Category:Solute carrier family]]
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{{membrane-protein-stub}}

Latest revision as of 08:49, 10 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Low affinity cationic amino acid transporter 2 is a protein that in humans is encoded by the SLC7A2 gene.[1][2]


See also

References

  1. ↑ Hoshide R, Ikeda Y, Karashima S, Matsuura T, Komaki S, Kishino T, Niikawa N, Endo F, Matsuda I (Mar 1997). "Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2)". Genomics. 38 (2): 174–8. doi:10.1006/geno.1996.0613. PMID 8954799.
  2. ↑ "Entrez Gene: SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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