Paroxysmal nocturnal hemoglobinuria physical examination: Difference between revisions
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{{ Paroxysmal nocturnal hemoglobinuria | {{Paroxysmal nocturnal hemoglobinuria}} | ||
{{CMG}} {{shyam}}; {{AE}} {{AEL}} | |||
==Overview== | ==Overview== | ||
Patients with paroxysmal nocturnal hemoglobinuria usually appear tired. Physical examination of patients with PNH is usually remarkable for [[fever]], [[Pallor|skin pallor]], [[Ecchymoses|skin ecchymoses]] and [[skin nodules]]. Physical examination may show [[abdominal distension]] if PNH is associated with [[Budd-Chiari syndrome]]. | |||
==Physical Examination== | ==Physical Examination== | ||
===Appearance of the Patient=== | |||
*Patients with paroxysmal nocturnal hemoglobinuria usually appear tired | |||
===Vital Signs=== | |||
*Fever may be present due to infections | |||
===Skin=== | |||
* [[Pallor]] | |||
* Skin ecchymoses | |||
* Skin nodules if it is associated with dermal vein thrombosis | |||
===HEENT=== | |||
* Mucosal pallor | |||
===Neck=== | |||
* Neck examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal | |||
===Lungs=== | |||
* Pulmonary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal | |||
===Heart=== | |||
* Cardiovascular examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal | |||
===Abdomen=== | ===Abdomen=== | ||
*[[Abdominal distention]] if associated with [[Budd-Chiari syndrome]]<ref name="pmid27326316">{{cite journal| author=Shin N, Kim YH, Xu H, Shi HB, Zhang QQ, Colon Pons JP et al.| title=Redefining Budd-Chiari syndrome: A systematic review. | journal=World J Hepatol | year= 2016 | volume= 8 | issue= 16 | pages= 691-702 | pmid=27326316 | doi=10.4254/wjh.v8.i16.691 | pmc=4909431 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27326316 }} </ref> | |||
*[[Hepatomegaly]] | |||
*[[Splenomegaly]] | |||
===Genitourinary=== | |||
* Genitourinary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: (name of the system)]] | |||
Latest revision as of 19:43, 18 December 2018
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Paroxysmal nocturnal hemoglobinuria Microchapters |
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Differentiating Paroxysmal nocturnal hemoglobinuria from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [3]
Overview
Patients with paroxysmal nocturnal hemoglobinuria usually appear tired. Physical examination of patients with PNH is usually remarkable for fever, skin pallor, skin ecchymoses and skin nodules. Physical examination may show abdominal distension if PNH is associated with Budd-Chiari syndrome.
Physical Examination
Appearance of the Patient
- Patients with paroxysmal nocturnal hemoglobinuria usually appear tired
Vital Signs
- Fever may be present due to infections
Skin
- Pallor
- Skin ecchymoses
- Skin nodules if it is associated with dermal vein thrombosis
HEENT
- Mucosal pallor
Neck
- Neck examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
Lungs
- Pulmonary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
Heart
- Cardiovascular examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
Abdomen
- Abdominal distention if associated with Budd-Chiari syndrome[1]
- Hepatomegaly
- Splenomegaly
Genitourinary
- Genitourinary examination of patients with paroxysmal nocturnal hemoglobinuria is usually normal
References
- ↑ Shin N, Kim YH, Xu H, Shi HB, Zhang QQ, Colon Pons JP; et al. (2016). "Redefining Budd-Chiari syndrome: A systematic review". World J Hepatol. 8 (16): 691–702. doi:10.4254/wjh.v8.i16.691. PMC 4909431. PMID 27326316.