Sandbox subdural empyema: Difference between revisions

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==Antimicrobial Regimen – Empiric Therapy==
==Antimicrobial Regimen – Empiric Therapy==
{{rx|Infants < 1 month}}
{{rx|Infants < 1 month}}
* Ampicillin 200 mg/kg/day IV q4h {{and}}
* [[Ampicillin]] 200 mg/kg/day IV q4h {{and}}
* Cefotaxime 200 mg/kg/day IV q6h
* [[Cefotaxime]] 200 mg/kg/day IV q6h
</li>
</li>
{{rx|Infants 1–3 months}}
{{rx|Infants 1–3 months}}
* Ampicillin 200 mg/kg/day IV q4h {{and}}
* [[Ampicillin]] 200 mg/kg/day IV q4h {{and}}
* Cefotaxime 200 mg/kg/day IV q6h {{or}} Ceftriaxone 100 mg/kg/day IV q12h
* [[Cefotaxime]] 200 mg/kg/day IV q6h {{or}} [[Ceftriaxone]] 100 mg/kg/day IV q12h
</li>
</li>
{{rx|Infants > 3 months or adults < 55 years (immunocompetent)}}
{{rx|Infants &gt; 3 months or adults &lt; 55 years}}
* Ampicillin 200 mg/kg/day IV, q4h {{and}}
* [[Vancomycin]] 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) {{and}}
* Cefotaxime 200 mg/kg/day IV, q6h
* [[Cefotaxime]] 200 mg/kg/day IV q6h (pediatric) or 12 g/day IV q4h (adult) {{or}} [[Ceftriaxone]] 100 mg/kg/day IV q12h (pediatric) or 4 g/day IV q12h (adult) {{or}} [[Cefepime]] 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult)
</li>
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{{rx|Adults ≥ 55 years, alcoholics, or with debilitating illness}}
{{rx|Adults ≥ 55 years, alcoholics, or with debilitating illness}}
* Ampicillin 200 mg/kg/day IV, q4h {{and}}
* [[Ampicillin]] 200 mg/kg/day IV q4h {{and}}
* Cefotaxime 200 mg/kg/day IV, q6h
* [[Vancomycin]] 2 g/day IV q12h {{and}}
* [[Cefotaxime]] 12 g/day IV q4h {{or}} [[Ceftriaxone]] 4 g/day IV q12h {{or}} [[Cefepime]] 6 g/day IV q8h
</li>
</li>
{{rx|Impaired cell-mediated immunity or hospital-acquired, post-neurosurgery, or post-traumatic meningitis}}
{{rx|Impaired cell-mediated immunity or hospital-acquired, post-neurosurgery, or post-traumatic meningitis}}
* Ampicillin 200 mg/kg/day IV, q4h {{and}}
* [[Ampicillin]] 200 mg/kg/day IV q4h (pediatric) or 12 g/day IV q4h (adult) {{and}}
* Cefotaxime 200 mg/kg/day IV, q6h
* [[Vancomycin]] 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) {{and}}
* [[Ceftazidime]] 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult) {{or}} [[Meropenem]] 20 mg/kg/day IV q8h (pediatric) or 3 g/day IV q8h (adult)
</li>
</li>

Latest revision as of 17:49, 27 April 2015

Antimicrobial Regimen – Empiric Therapy

    • Vancomycin 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) AND
    • Cefotaxime 200 mg/kg/day IV q6h (pediatric) or 12 g/day IV q4h (adult) OR Ceftriaxone 100 mg/kg/day IV q12h (pediatric) or 4 g/day IV q12h (adult) OR Cefepime 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult)
    • Ampicillin 200 mg/kg/day IV q4h (pediatric) or 12 g/day IV q4h (adult) AND
    • Vancomycin 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) AND
    • Ceftazidime 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult) OR Meropenem 20 mg/kg/day IV q8h (pediatric) or 3 g/day IV q8h (adult)