Sandbox subdural empyema: Difference between revisions

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(Created page with "==Antimicrobial Regimen – Empiric Therapy== ===Infants < 1 month=== ===Infants 1–3 months=== ===Infants > 3 months or adults < 55 years (immunocompetent)=== ===...")
 
 
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==Antimicrobial Regimen – Empiric Therapy==
==Antimicrobial Regimen – Empiric Therapy==
 
{{rx|Infants &lt; 1 month}}
 
* [[Ampicillin]] 200 mg/kg/day IV q4h {{and}}
 
* [[Cefotaxime]] 200 mg/kg/day IV q6h
===Infants < 1 month===
 
 
 
===Infants 1–3 months===
 
 
===Infants > 3 months or adults < 55 years (immunocompetent)===
 
 
 
===Adults ≥ 55 years, alcoholics, or with debilitating illness===
 
 
 
 
===Hospital-acquired, post-neurosurgery, or post-traumatic meningitis; impaired cell-mediated immunity, neutropenia===
 
 
 
 
 
 
 
 
 
 
{{rx|Preferred Regimen}}
* [[Ciprofloxacin]] 400 mg IV q8h
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{{rx|Alternative Regimen}}
{{rx|Infants 1–3 months}}
* [[Piperacillin-Tazobacbam]] 3.375g IV q4h {{and}}
* [[Ampicillin]] 200 mg/kg/day IV q4h {{and}}
* [[Tobramycin]] 3–5 mg/kg/day IV q8h
* [[Cefotaxime]] 200 mg/kg/day IV q6h {{or}} [[Ceftriaxone]] 100 mg/kg/day IV q12h
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{{rx|Other Regimens for Susceptible Pseudomonas}}
{{rx|Infants &gt; 3 months or adults &lt; 55 years}}
* [[Imipenem]] 0.5 g IV q6h {{or}} [[Meropenem]] 1 g IV q8h {{or}} [[Cefepime]] 2 g IV q12h {{or}} [[Ceftazidime]] 2 g IV q8h
* [[Vancomycin]] 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) {{and}}
* [[Cefotaxime]] 200 mg/kg/day IV q6h (pediatric) or 12 g/day IV q4h (adult) {{or}} [[Ceftriaxone]] 100 mg/kg/day IV q12h (pediatric) or 4 g/day IV q12h (adult) {{or}} [[Cefepime]] 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult)
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{{rx|Adults ≥ 55 years, alcoholics, or with debilitating illness}}
* [[Ampicillin]] 200 mg/kg/day IV q4h {{and}}
* [[Vancomycin]] 2 g/day IV q12h {{and}}
* [[Cefotaxime]] 12 g/day IV q4h {{or}} [[Ceftriaxone]] 4 g/day IV q12h {{or}} [[Cefepime]] 6 g/day IV q8h
</li>
{{rx|Impaired cell-mediated immunity or hospital-acquired, post-neurosurgery, or post-traumatic meningitis}}
* [[Ampicillin]] 200 mg/kg/day IV q4h (pediatric) or 12 g/day IV q4h (adult) {{and}}
* [[Vancomycin]] 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) {{and}}
* [[Ceftazidime]] 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult) {{or}} [[Meropenem]] 20 mg/kg/day IV q8h (pediatric) or 3 g/day IV q8h (adult)
</li>
</li>

Latest revision as of 17:49, 27 April 2015

Antimicrobial Regimen – Empiric Therapy

    • Vancomycin 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) AND
    • Cefotaxime 200 mg/kg/day IV q6h (pediatric) or 12 g/day IV q4h (adult) OR Ceftriaxone 100 mg/kg/day IV q12h (pediatric) or 4 g/day IV q12h (adult) OR Cefepime 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult)
    • Ampicillin 200 mg/kg/day IV q4h (pediatric) or 12 g/day IV q4h (adult) AND
    • Vancomycin 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) AND
    • Ceftazidime 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult) OR Meropenem 20 mg/kg/day IV q8h (pediatric) or 3 g/day IV q8h (adult)