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In enzymology, a xylono-1,4-lactonase (EC is an enzyme that catalyzes the chemical reaction

D-xylono-1,4-lactone + H2O D-xylonate

Thus, the two substrates of this enzyme are D-xylono-1,4-lactone and H2O, whereas its product is D-xylonate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is D-xylono-1,4-lactone lactonohydrolase. Other names in common use include xylono-g-lactonase, and xylonolactonase. This enzyme participates in pentose and glucuronate interconversions.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Buchert J and Viikari L (1988). "The role of xylonolactone in xylonic acid production by Pseudomonas fragi". Appl. Microbiol. Biotechnol. 27: 333&ndash, 336.

External links

Gene Ontology (GO) codes