Vasa recta

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Artery: Vasa recta
A nephron, the vasa recta is labelled arteria recta
Latin	arteriolae rectae renis
Gray's	subject #253 1224
Source	Arcuate arteries of the kidney, efferent arteriole
Branches	Straight venules of kidney, arcuate vein
Dorlands / Elsevier	a_62/12156708

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For the intestinal structure, see Vasa recta (intestines)

In the blood supply of the kidney, the vasa recta renis (or straight arteries of kidney, or straight arterioles of kidney) form a series of straight capillaries (recta is from the Latin for "straight") that descend from the cortex into the medulla.

These vessels branch off of the efferent arterioles of juxtamedullary nephrons (those nephrons closest to the medulla), enter the medulla, and surround the loop of Henle.

Histology

On a slide, vasa recta can be distinguished from the tubules of the loop of Henle by the presence of blood.^[1]

Function

Each of the vasa recta has a hairpin turn in the medulla and carries blood at a very slow rate, two factors crucial in the maintenance of countercurrent exchange that prevent washout of the concentration gradients established in the renal medulla.^[2]

The maintenance of this concentration gradient is one of the components responsible for the kidney's ability to produce concentrated urine.

Nomenclature

According to Terminologia Anatomica^[3], the term "vasa recta renis" is an alternate name for "arteriolae rectae renis", and a separate term, venulae rectae renis, is used to identify the venous portion.

However, other sources consider "vasa recta renis" to refer to both the arterial and venous portions.^[4]

The "renis" is often omitted, but there do exist two other structures with the same name:

• vasa recta (intestines) (in the ileum and jejunum)^[5]
• the straight portion of the seminiferous tubule^[6]

Pathology

The slow blood flow in vasa recta makes them a likely place of thrombosis in hypercoagulable states, or erythrocyte sickling in sickle cell disease. Ischemia that results may lead to renal papillary necrosis.

References

1. ↑ Histology at Boston University 15802loa
2. ↑ Physiology at MCG 7/7ch08/7ch08p07
3. ↑ a_62/12156708 at Dorland's Medical Dictionary
4. ↑ Histology at Boston University 15804loa
5. ↑ Norman/Georgetown jejunumileum
6. ↑ vasa+recta at eMedicine Dictionary

External links

• UIUC Histology Subject 937
• UMLS

v • d • e Urinary system - Kidney
Layers	Renal fascia • Renal capsule • Renal cortex  (Renal column) • Renal medulla (Renal sinus, Renal pyramids, medullary interstitium) • Renal lobe • Cortical lobule • Medullary ray • Nephron
Afferent circulation	Renal artery → Segmental arteries → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Renal corpuscle (Glomerulus, Bowman's capsule)
Renal tubule	Proximal tubule → Loop of Henle (Descending, Thin ascending, Thick ascending) → Distal convoluted tubule → Connecting tubule → Collecting ducts → Duct of Bellini → Renal papilla → Minor calyx → Major calyx → Renal pelvis → Ureter
Efferent circulation	Glomerulus → Efferent arterioles → Peritubular capillaries/Vasa recta → Arcuate vein → Interlobar veins → Renal vein
Juxtaglomerular apparatus	Macula densa • Juxtaglomerular cells • Extraglomerular mesangial cell
Filtration	Glomerular basement membrane • Podocyte • Filtration slits • Intraglomerular mesangial cell • Tubular fluid
Renal physiology	Acid base physiology • Fluid balance

v • d • e WikiDoc Research Resources for Vasa recta
Articles on Vasa recta	Most recent articles on Vasa recta • Most cited articles on Vasa recta • Review articles on Vasa recta • Articles on Vasa recta in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Vasa recta	Powerpoint slides on Vasa recta • Images of Vasa recta • Photos of Vasa recta • Podcasts & MP3s on Vasa recta • Videos on Vasa recta
Evidence Based Medicine Regarding Vasa recta	Cochrane Collaboration on Vasa recta • Bandolier on Vasa recta • TRIP on Vasa recta
Cost Effectiveness of Vasa recta	Cost Effectiveness of Vasa recta
Clinical Trials Involving Vasa recta	Ongoing Trials on Vasa recta at Clinical Trials.gov • Trial results on Vasa recta • Clinical Trials on Vasa recta at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Vasa recta	US National Guidelines Clearinghouse on Vasa recta • NICE Guidance on Vasa recta • NHS PRODIGY Guidance • FDA on Vasa recta • CDC on Vasa recta
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Pharmacology Resources on Vasa recta	Dosing of Vasa recta • Drug interactions with Vasa recta • Side effects of Vasa recta • Allergic reactions to Vasa recta • Overdose information on Vasa recta • Carcinogenicity information on Vasa recta • Vasa recta in pregnancy • Pharmacokinetics of Vasa recta •
Genetics, Pharmacogenomics, and Proteinomics of Vasa recta	Genetics of Vasa recta • Pharmacogenomics of Vasa recta • Proteomics of Vasa recta
Newstories on Vasa recta	Vasa recta in the news • Be alerted to news on Vasa recta • News trends on Vasa recta
Commentary on Vasa recta	Blogs on Vasa recta
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Healthcare Provider Resources on Vasa recta	Symptoms of Vasa recta • Causes & Risk Factors for Vasa recta • Diagnostic studies for Vasa recta • Treatment of Vasa recta
Continuing Medical Education (CME) Programs on Vasa recta	CME Programs on Vasa recta
International Resources on Vasa recta	Vasa recta en Espanol • Vasa recta en Francais
Business Resources on Vasa recta	Vasa recta in the Marketplace • Patents on Vasa recta
Informatics Resources on Vasa recta	List of terms related to Vasa recta