Tyloxapol

Tyloxapol

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	R05CA01 (WHO)
Identifiers
IUPAC name formaldehyde;oxirane;4-(2,4,4-trimethylpentan-2-yl)phenol
CAS Number	25301-02-4 Y
PubChem CID	71388
DrugBank	DB06439 N
ChemSpider	11052515 N
UNII	Y27PUL9H56
KEGG	D03261 N
ChEMBL	ChEMBL1201548 N
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	(C15H21O(C2H4O)m)n
Molar mass	variable
NY (what is this?)  (verify)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent(containing mucus and pus) bronchopulmonary secretions, or with a stream of oxygen.

With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.

Tyloxapol is the main active ingredient of the medical device Tacholiquin. Tacholiquin is an Expectorant designated for inhalation and instillation reaching the upper and lower airways. Other brand names of pharmaceutical products containing Tyloxpol are: Exosurf, Alevaire