- L-tryptophan + H2O indole + pyruvate + NH3
This enzyme belongs to the family of lyases, specifically in the "catch-all" class of carbon-carbon lyases. The systematic name of this enzyme class is L-tryptophan indole-lyase (deaminating; pyruvate-forming). Other names in common use include L-tryptophanase, and L-tryptophan indole-lyase (deaminating). This enzyme participates in tryptophan metabolism and nitrogen metabolism. It has 2 cofactors: pyridoxal phosphate, and Potassium.
- IUBMB entry for 126.96.36.199
- BRENDA references for 188.8.131.52 (Recommended.)
- PubMed references for 184.108.40.206
- PubMed Central references for 220.127.116.11
- Google Scholar references for 18.104.22.168
- BURNS RO, DEMOSS RD (1962). "Properties of tryptophanase from Escherichia coli". Biochim. Biophys. Acta. 65: 233&ndash, 44. PMID 14017164.
- Cowell JL, Maser K and DeMoss, RD (1973). "Tryptophanase from Aeromonas liquifaciens. Purification, molecular weight and some chemical, catalytic and immunological properties". Biochim. Biophys. Acta. 315: 449&ndash, 463.
- NEWTON WA, MORINO Y, SNELL EE (1965). "PROPERTIES OF CRYSTALLINE TRYPTOPHANASE". J. Biol. Chem. 240: 1211&ndash, 8. PMID 14284727.
- The CAS registry number for this enzyme class is 9024-00-4.
Gene Ontology (GO) codes
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