Toxoplasmosis MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

Toxoplasmic encephalitis is the most common cause of intracerebral mass lesions and is thought to be caused by reactivation of chronic infection. Typically cerebral toxoplasmosis manifest as multiple lesions, with a predilection for the basal ganglia, thalami, and corticomedullary junction. Intracerebral mass lesions can be diagnosed using MRI scan. Findings include hyperintense (necrotising encephalitis) to isointense lesions(organising abscess), with surrounding perilesional oedema and often demonstrate ring enhancement or nodular enhancement.[1]

MRI

Toxoplasmic encephalitis is the most common cause of intracerebral mass lesions and is thought to be caused by reactivation of chronic infection. Typically cerebral toxoplasmosis manifest as multiple lesions, with a predilection for the basal ganglia, thalami, and corticomedullary junction. Intracerebral mass lesions can be diagnosed using MRI scan. [1] Findings include

  • Intensity is variable, from hyperintense to isointense
  • Hyperintense: thought to represent necrotising encephalitis
  • Isointense: thought to represent organising abscess
  • Lesions are surrounded by perilesional oedema
  • Lesions often demonstrate ring enhancement or nodular enhancement

References

  1. 1.0 1.1 Helton KJ, Maron G, Mamcarz E, Leventaki V, Patay Z, Sadighi Z (2016). "Unusual magnetic resonance imaging presentation of post-BMT cerebral toxoplasmosis masquerading as meningoencephalitis and ventriculitis". Bone Marrow Transplant. 51 (11): 1533–1536. doi:10.1038/bmt.2016.168. PMID 27348541.


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