- thymidine + phosphate thymine + 2-deoxy-alpha-D-ribose 1-phosphate
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is thymidine:phosphate deoxy-alpha-D-ribosyltransferase. Other names in common use include pyrimidine phosphorylase, thymidine-orthophosphate deoxyribosyltransferase, animal growth regulators, blood platelet-derived endothelial cell, growth factors, blood platelet-derived endothelial cell growth factor, deoxythymidine phosphorylase, gliostatins, pyrimidine deoxynucleoside phosphorylase, and thymidine:phosphate deoxy-D-ribosyltransferase. This enzyme participates in 3 metabolic pathways: purine metabolism, pyrimidine metabolism, and bladder cancer.
- IUBMB entry for 18.104.22.168
- BRENDA references for 22.214.171.124 (Recommended.)
- PubMed references for 126.96.36.199
- PubMed Central references for 188.8.131.52
- Google Scholar references for 184.108.40.206
- FRIEDKIN M, ROBERTS D (1954). "The enzymatic synthesis of nucleosides. I. Thymidine phosphorylase in mammalian tissue". J. Biol. Chem. 207: 245&ndash, 56. PMID 13152099.
- Zimmerman M and Seidenberg J (1964). "Deoxyribosyl transfer. I. Thymidine phosphorylase and nucleoside deoxyribosyltransferase in normal and malignant tissues". J. Biol. Chem. 239: 2618&ndash, 2621.
- Zimmerman M (1964). "Deoxyribosyl transfer. II. Nucleoside:pyrimidine deoxyribosyltransferase activity of three partially purified thymidine phosphorylases". J. Biol. Chem. 239: 2622&ndash, 2627.
- The CAS registry number for this enzyme class is 9030-23-3.
Gene Ontology (GO) codes
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