Tetracycline (topical)

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Tetracycline (topical)
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

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Overview

Tetracycline (topical) is an antibiotic that is FDA approved for the treatment of first aid to help prevent infection in minor cuts, scrapes, and burns. Common adverse reactions include anorexia, nausea, epigastric distress, vomiting, diarrhea, glossitis, black hairy tongue, dysphagia, enterocolitis, and inflammatory lesions (with monilial overgrowth) in the anogenital region.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

  • first aid to help prevent infection in minor:

Directions

  • clean the affected area
  • hold the tube gently, with swab handle facing upward, pinch tube firmly at dotted line. With other hand, grasp applicator handle at base.
  • bend gently down until seal is broken, twist gently until handle separates from tube
  • use EasySnap™ handle to pull swab from tube
  • apply a small amount of this product (an amount equal to the surface area of the tip of a finger) on the area 1 to 3 times daily
  • may be covered with a sterile bandage
  • discard swab applicator after use

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Tetracycline (topical) in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Tetracycline (topical) in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Tetracycline (topical) in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Tetracycline (topical) in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Tetracycline (topical) in pediatric patients.

Contraindications

There is limited information regarding Tetracycline (topical) Contraindications in the drug label.

Warnings

  • For external use only
  • DO NOT USE
  • if you are allergic to any of the ingredients
  • Pin the eyes
  • over large areas of the body
  • ASK A DOCTOR BEFORE USE IF YOU HAVE
  • deep or puncture wounds
  • animal bites
  • serious burns
  • STOP USE AND ASK A DOCTOR IF
  • you need to use longer than 1 week
  • condition persists or gets worse
  • rash or other allergic reaction develop
  • KEEP OUT OF REACH OF CHILDREN.
  • If swallowed, get medical help or contact a Poison Control Center right away.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Tetracycline (topical) in the drug label.

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Tetracycline (topical) in the drug label.

Drug Interactions

There is limited information regarding Tetracycline (topical) Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): D There is no FDA guidance on usage of Tetracycline (topical) in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Tetracycline (topical) in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Tetracycline (topical) during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Tetracycline (topical) with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Tetracycline (topical) with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Tetracycline (topical) with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Tetracycline (topical) with respect to specific gender populations.

Race

There is no FDA guidance on the use of Tetracycline (topical) with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Tetracycline (topical) in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Tetracycline (topical) in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Tetracycline (topical) in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Tetracycline (topical) in patients who are immunocompromised.

Administration and Monitoring

Administration

Monitoring

There is limited information regarding Monitoring of Tetracycline (topical) in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Tetracycline (topical) in the drug label.

Overdosage

There is limited information regarding Chronic Overdose of Tetracycline (topical) in the drug label.

Pharmacology

Template:Px
Tetracycline (topical)
Systematic (IUPAC) name
?
Identifiers
CAS number 60-54-8

64-75-5 (hydrochloride)
ATC code A01AB13 D06AA04 (WHO) J01AA07 (WHO) S01AA09 (WHO) S02AA08 (WHO) S03AA02 (WHO) Template:ATCvet Template:ATCvet Template:ATCvet
PubChem 643969
DrugBank DB00759
Chemical data
Formula Template:OrganicBox atomTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox 
Mol. mass 444.435 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability 75%
Metabolism Not metabolised
Half life 8-11 hours, 57-108 hours (kidney impairment)
Excretion Urine (>60%), feces
Therapeutic considerations
Licence data

US

Pregnancy cat.

D(AU) D(US)

Legal status

Template:Unicode Prescription only

Routes oral, topical (skin and eye), intramuscular, intravenous

Mechanism of Action

There is limited information regarding Tetracycline (topical) Mechanism of Action in the drug label.

Structure

There is limited information regarding Tetracycline (topical) Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Tetracycline (topical) in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Tetracycline (topical) in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Tetracycline (topical) in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Tetracycline (topical) in the drug label.

How Supplied

  • tamper evident: safety sealed swabs. Do not use if seal has been broken.
  • store at room temperature 20-25°C (68-77°F)

Storage

There is limited information regarding Tetracycline (topical) Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

There is limited information regarding Patient Counseling Information of Tetracycline (topical) in the drug label.

Precautions with Alcohol

  • Alcohol-Tetracycline (topical) interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

Look-Alike Drug Names

There is limited information regarding Tetracycline (topical) Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. "DIABECLINE - tetracycline hydrochloride ointment".


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