TUBB3

Tubulin, beta 3
File:PBB Protein TUBB3 image.jpg PDB rendering based on 1ffx.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1ffx​, 1ia0​, 1jff​, 1sa0​, 1sa1​, 1tub​, 1tvk​, 1z2b​, 2hxf​, 2hxh​
Identifiers
Symbols	TUBB3 ; MC1R; TUBB4; beta-4
External IDs	Template:OMIM5 Template:MGI HomoloGene: 68503
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Tubulin, beta 3, also known as TUBB3, is a human gene.

Further reading

• Venter JC (1993). "Identification of new human receptor and transporter genes by high throughput cDNA (EST) sequencing". J. Pharm. Pharmacol. 45 Suppl 1: 355–60. PMID 8098743.
• Burgoyne RD, Cambray-Deakin MA, Lewis SA; et al. (1989). "Differential distribution of beta-tubulin isotypes in cerebellum". EMBO J. 7 (8): 2311–9. PMID 2461292.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vinores SA, Derevjanik NL, Mahlow J; et al. (1995). "Class III beta-tubulin in human retinal pigment epithelial cells in culture and in epiretinal membranes". Exp. Eye Res. 60 (4): 385–400. PMID 7789418.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
• Khan IA, Ludueña RF (1996). "Phosphorylation of beta III-tubulin". Biochemistry. 35 (12): 3704–11. doi:10.1021/bi951247p. PMID 8619990.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ranganathan S, Dexter DW, Benetatos CA, Hudes GR (1998). "Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents". Biochim. Biophys. Acta. 1395 (2): 237–45. PMID 9473684.CS1 maint: Multiple names: authors list (link)
• Watts NR, Sackett DL, Ward RD; et al. (2000). "HIV-1 rev depolymerizes microtubules to form stable bilayered rings". J. Cell Biol. 150 (2): 349–60. PMID 10908577.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sánchez Más J, Olivares Sánchez C, Ghanem G; et al. (2003). "Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function". Eur. J. Biochem. 269 (24): 6133–41. PMID 12473109.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen D, Wang M, Zhou S, Zhou Q (2004). "HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim". EMBO J. 21 (24): 6801–10. PMID 12486001.CS1 maint: Multiple names: authors list (link)
• Rosell R, Scagliotti G, Danenberg KD; et al. (2003). "Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer". Oncogene. 22 (23): 3548–53. doi:10.1038/sj.onc.1206419. PMID 12789263.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hari M, Yang H, Zeng C; et al. (2004). "Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel". Cell Motil. Cytoskeleton. 56 (1): 45–56. doi:10.1002/cm.10132. PMID 12905530.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Campbell GR, Pasquier E, Watkins J; et al. (2005). "The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis". J. Biol. Chem. 279 (46): 48197–204. doi:10.1074/jbc.M406195200. PMID 15331610.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mozzetti S, Ferlini C, Concolino P; et al. (2005). "Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients". Clin. Cancer Res. 11 (1): 298–305. PMID 15671559.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• de Mareuil J, Carre M, Barbier P; et al. (2006). "HIV-1 Tat protein enhances microtubule polymerization". Retrovirology. 2: 5. doi:10.1186/1742-4690-2-5. PMID 15691386.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Giacca M (2006). "HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?". Retrovirology. 2: 7. doi:10.1186/1742-4690-2-7. PMID 15698476.