Substitution (chemistry)

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Substitution in the context of organic chemistry has the general meaning of replacing an atom, a functional group, or a substituent in a molecule.

Substituted compounds

Substituted compounds are chemical compounds where one or more hydrogen atoms of a core structure have been replaced with a functional group like alkyl, hydroxy, or halogen.


Benzene is a simple aromatic ring. Substituted benzenes are a heterogeneous group of chemicals with a wide spectrum of uses and properties:

Substitution reaction

A substitution reaction is a general type of organic reaction where one functional group or substituent in the reactant molecule is replaced by another. Common types of substitution reactions are:

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