Streptomyces achromogenes
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| Streptomyces achromogenes | ||||||||||||
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| Streptomyces achromogenes Okami and Umezawa 1953 |
Streptomyces achromogenes is a species of gram-positive bacterium that belongs in the genus Streptomyces. S. achromogenes can be grown at 26°C in a medium of yeast and malt extract with glucose[citation needed].
S. achromogenes is the source of the restriction enzymes SacI and SacII,[1] as well as the antibiotic compound sarcidin.[2] A strain of the bacterium called S. achromogenes var. streptozoticus was the original source of the pancreatic cancer drug streptozotocin.[3]
References
- ↑ Zhuravleva L, Oreshkin E, Bezborodov A (1987). "Isolation and purification of restriction endonuclease SacI from Streptomyces achromogenes ATCC 12767". Prikl Biokhim Mikrobiol. 23 (2): 208–15. PMID 3033630.
- ↑ Takeuchi T, Nitta K, Umezawa H (1953). "On an antibiotic, sarcidin, produced by Streptomyces n. sp. S. achromogenes". J Antibiot (Tokyo). 6 (1): 31–2. PMID 13061372.
- ↑ Bolzán A, Bianchi M (2002). "Genotoxicity of streptozotocin". Mutat Res. 512 (2–3): 121–34. PMID 12464347.