Sitafloxacin

Sitafloxacin

Clinical data
Routes of administration	Oral
ATC code	J01MA21 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid
CAS Number	127254-12-0 N
PubChem CID	461399
ChemSpider	405945 Y
UNII	3GJC60U4Q8
ChEMBL	ChEMBL108821 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C19H18ClF2N3O3
Molar mass	409.81
3D model (JSmol)	Interactive image
SMILES F[C@H]5C[C@H]5N2/C=C(/C(=O)O)C(=O)c1cc(F)c(c(Cl)c12)N4C[C@@H](N)C3(CC3)C4
InChI InChI=1S/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1 Y Key:PNUZDKCDAWUEGK-CYZMBNFOSA-N Y
NY (what is this?)  (verify)

WikiDoc Resources for Sitafloxacin
Articles
Most recent articles on Sitafloxacin Most cited articles on Sitafloxacin Review articles on Sitafloxacin Articles on Sitafloxacin in N Eng J Med, Lancet, BMJ
Media
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Evidence Based Medicine
Cochrane Collaboration on Sitafloxacin Bandolier on Sitafloxacin TRIP on Sitafloxacin
Clinical Trials
Ongoing Trials on Sitafloxacin at Clinical Trials.gov Trial results on Sitafloxacin Clinical Trials on Sitafloxacin at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Sitafloxacin NICE Guidance on Sitafloxacin NHS PRODIGY Guidance FDA on Sitafloxacin CDC on Sitafloxacin
Books
Books on Sitafloxacin
News
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Commentary
Blogs on Sitafloxacin
Definitions
Definitions of Sitafloxacin
Patient Resources / Community
Patient resources on Sitafloxacin Discussion groups on Sitafloxacin Patient Handouts on Sitafloxacin Directions to Hospitals Treating Sitafloxacin Risk calculators and risk factors for Sitafloxacin
Healthcare Provider Resources
Symptoms of Sitafloxacin Causes & Risk Factors for Sitafloxacin Diagnostic studies for Sitafloxacin Treatment of Sitafloxacin
Continuing Medical Education (CME)
CME Programs on Sitafloxacin
International
Sitafloxacin en Espanol Sitafloxacin en Francais
Business
Sitafloxacin in the Marketplace Patents on Sitafloxacin
Experimental / Informatics
List of terms related to Sitafloxacin

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.

See also

• Quinolone

Further reading

• Keating GM (April 2011). "Sitafloxacin: in bacterial infections". Drugs. 71 (6): 731–44. doi:10.2165/11207380-000000000-00000. PMID 21504249.

External links

• Template:Ja icon Gracevit グレースビット (PDF) Daiichi Sankyo Co. January 2008.