Sandbox: Multiple pulmonary nodule causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Luke Rusowicz-Orazem, B.S.

Overview

Causes of multiple pulmonary nodules may be classified into 5 categories: infectious, neoplastic, inflammatory, immunological, vascular, and miscellaneous.^[1]^[1]

Causes

Common Causes

Common malignant causes of multiple pulmonary nodules include:^[2]

Primary lung cancer

Common benign causes of multiple pulmonary nodules include:^[1]

Causes by Organ System

Cardiovascular	Arteriovenous malformation, Infarction zone, Pulmonary arterio-venous malformation, Pulmonary embolism, Pulmonary infarction
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	Thyroid cancer
Environmental	Black lung disease
Gastroenterologic	Gastric cancer
Genetic	No underlying causes
Hematologic	Aneurysm of the pulmonary artery, Hemangioma, Hematoma, Non-hodgkin lymphoma, Pulmonary hamartoma
Iatrogenic	No underlying causes
Infectious Disease
Musculoskeletal/Orthopedic	Multiple myeloma
Neurologic	Aneurysm of the pulmonary artery, Arteriovenous malformation, Neurofibroma, Neurogenic tumor
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	Breast cancer
Oncologic	Adenocarcinoma , Blastoma, Bronchial adenoma, Cancers, Carcinoid tumor, Chondroma, Fibroma, Gastric cancer, Granuloma, Hamartoma, Hamartomatosis, Hemangioma, Hypernephroma, Large cell lung carcinoma, Lung metastases, Lymphoma, Metastasis, Multiple myeloma, Neurofibroma, Neurogenic tumor, Non-hodgkin lymphoma, Non-small cell lung cancer, Primary lung cancer, Prostate cancer, Pulmonary inflammatory pseudotumor, Pulmonary sarcoma, Pulmonary sequestration, Sarcoma, Seminoma, Small cell lung cancer, Squamous cell carcinoma, Thyroid cancer
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	Black lung disease, Bronchial adenoma, Bronchogenic carcinoma, Bronchogenic cyst, Churg-strauss syndrome, Large cell lung carcinoma, Lung metastases, Non-small cell lung cancer, Primary lung cancer, Pulmonary embolism, Pulmonary infarction, Pulmonary sarcoma, Sarcoidosis, Small cell lung cancer, Squamous cell carcinoma, Wegener's granulomatosis
Renal/Electrolyte	Hypernephroma
Rheumatology/Immunology/Allergy	Amyloidosis, Churg-strauss syndrome, Fibroma, Granuloma, Immunological, Progressive massive fibrosis, Rheumatoid arthritis, Rheumatoid disease, Sarcoidosis, Wegener's granulomatosis
Sexual	No underlying causes
Trauma
Urologic	Prostate cancer
Miscellaneous	No underlying causes

Causes in Alphabetical Order

References

↑ ^1.0 ^1.1 ^1.2 Lillington GA (1991). "Management of solitary pulmonary nodules". Dis Mon. 37 (5): 271–318. PMID 2019220.
↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002: 306-307 ISBN 1591032016

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[pmid2019220-1] 1.0 ^1.1 ^1.2 Lillington GA (1991). "Management of solitary pulmonary nodules". Dis Mon. 37 (5): 271–318. PMID 2019220.

[DDX-2] Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002: 306-307 ISBN 1591032016

[1]

[2]