SLU7

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

Pre-mRNA-splicing factor SLU7 is a protein that in humans is encoded by the SLU7 gene.^[1]^[2]^[3]

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions.^[3]

References

↑ Chua K, Reed R (May 1999). "Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing". Genes Dev. 13 (7): 841–50. doi:10.1101/gad.13.7.841. PMC 316594. PMID 10197984.
↑ Shomron N, Alberstein M, Reznik M, Ast G (Mar 2005). "Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing". J Cell Sci. 118 (Pt 6): 1151–9. doi:10.1242/jcs.01720. PMID 15728250.
↑ ^3.0 ^3.1 "Entrez Gene: SLU7 SLU7 splicing factor homolog (S. cerevisiae)".

Alberstein M, Amit M, Vaknin K, et al. (2008). "Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing". RNA. 13 (11): 1988–99. doi:10.1261/rna.492907. PMC 2040095. PMID 17804646.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Shomron N, Reznik M, Ast G (2005). "Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus". Mol. Biol. Cell. 15 (8): 3782–95. doi:10.1091/mbc.E04-02-0152. PMC 491837. PMID 15181151.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Chua K, Reed R (2001). "An upstream AG determines whether a downstream AG is selected during catalytic step II of splicing". Mol. Cell. Biol. 21 (5): 1509–14. doi:10.1128/MCB.21.5.1509-1514.2001. PMC 86697. PMID 11238888.
Chua K, Reed R (2000). "The RNA splicing factor hSlu7 is required for correct 3' splice-site choice". Nature. 402 (6758): 207–10. doi:10.1038/46086. PMID 10647016.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[pmid10197984-1] Chua K, Reed R (May 1999). "Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing". Genes Dev. 13 (7): 841–50. doi:10.1101/gad.13.7.841. PMC 316594. PMID 10197984.

[pmid15728250-2] Shomron N, Alberstein M, Reznik M, Ast G (Mar 2005). "Stress alters the subcellular distribution of hSlu7 and thus modulates alternative splicing". J Cell Sci. 118 (Pt 6): 1151–9. doi:10.1242/jcs.01720. PMID 15728250.

[entrez-3] 3.0 ^3.1 "Entrez Gene: SLU7 SLU7 splicing factor homolog (S. cerevisiae)".

[1]

[2]

[3]

SLU7

References

Further reading

Navigation menu