SH3BP2

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SH3-domain binding protein 2
Identifiers
SymbolSH3BP2
Entrez6452
HUGO10825
OMIM602104
RefSeqNM_003023
UniProtP78314
Other data
LocusChr. 4 p16.3

SH3BP2 (SH3 domain-binding protein 2) is a protein that comes from a gene located on Chromosome 4. SH3BP2 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. It binds to phosphatidylinositols linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. It is also associated with cherubism.

See also

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