Retinyl-palmitate esterase

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In enzymology, a retinyl-palmitate esterase (EC is an enzyme that catalyzes the chemical reaction

retinyl palmitate + H2O retinol + palmitate

Thus, the two substrates of this enzyme are retinyl palmitate and H2O, whereas its two products are retinol and palmitate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is retinyl-palmitate palmitohydrolase. Other names in common use include retinyl palmitate hydrolase, retinyl palmitate hydrolyase, and retinyl ester hydrolase. This enzyme participates in retinol metabolism.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Mahadevan S, Ayyoub NI, Roels OA (1966). "Hydrolysis of retinol palmitate by rat liver". J. Biol. Chem. 241: 57&ndash, 64. PMID 5901057.

External links

The CAS registry number for this enzyme class is 9063-69-8.

Gene Ontology (GO) codes