Prothionamide

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Prothionamide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J04AD01 (WHO) ;
Identifiers
	IUPAC name 2-propylpyridine-4-carbothioamide;
CAS Number	14222-60-7 ;
PubChem CID	666418;
ChemSpider	579891 ;
UNII	76YOO33643;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C9H12N2S
Molar mass	180.271 g/mol
3D model (JSmol)	Interactive image;
	SMILES CCCc1cc(ccn1)C(=S)N;
	InChI InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) ; Key:VRDIULHPQTYCLN-UHFFFAOYSA-N ;
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis.^[1]

It has also been tested for use in the treatment of leprosy.^[2]

References

↑ Wang F, Langley R, Gulten G; et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". J. Exp. Med. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
↑ Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". Am. J. Trop. Med. Hyg. 74 (3): 457–61. PMID 16525107.

[pmid17227913-1] Wang F, Langley R, Gulten G; et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". J. Exp. Med. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.

[pmid16525107-2] Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". Am. J. Trop. Med. Hyg. 74 (3): 457–61. PMID 16525107.

[1]

[2]

v t e Antimycobacterials (J04)
Tuberculosis/ tuberculosis treatment	Aminosalicylic acid (Calcium aminosalicylate, Sodium aminosalicylate) Antibiotics (Amikacin, Capreomycin, Cycloserine, Kanamycin, Rifabutin, Rifampicin, Rifamycin, Rifapentin, Streptomycin) hydrazides (Isoniazid) thiocarbamides (Ethionamide, Protionamide, Tiocarlide) Others (Ethambutol, Morinamide, Pyrazinamide, Terizidone)
Leprosy	Aldesulfone sodium • Clofazimine • Dapsone • Rifampicin

Prothionamide

Overview

See also

References

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