Polyhexanide

Template:Chembox AbbreviationsTemplate:Chembox E number

Polyhexanide

Names
Other names Polyhexamethylene biguanide; Polyhexamethylene guanide; Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene); Poly(hexamethylenebiguanide); Polihexanide
Identifiers
CAS Number	28757-47-3 N 32289-58-0 (HCl) Y 28757-48-4 N
ChemSpider	NA Y
ECHA InfoCard
UNII	322U039GMF Y
Properties
Chemical formula	(C8H17N5)n
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

WikiDoc Resources for Polyhexanide
Articles
Most recent articles on Polyhexanide Most cited articles on Polyhexanide Review articles on Polyhexanide Articles on Polyhexanide in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Polyhexanide Images of Polyhexanide Photos of Polyhexanide Podcasts & MP3s on Polyhexanide Videos on Polyhexanide
Evidence Based Medicine
Cochrane Collaboration on Polyhexanide Bandolier on Polyhexanide TRIP on Polyhexanide
Clinical Trials
Ongoing Trials on Polyhexanide at Clinical Trials.gov Trial results on Polyhexanide Clinical Trials on Polyhexanide at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Polyhexanide NICE Guidance on Polyhexanide NHS PRODIGY Guidance FDA on Polyhexanide CDC on Polyhexanide
Books
Books on Polyhexanide
News
Polyhexanide in the news Be alerted to news on Polyhexanide News trends on Polyhexanide
Commentary
Blogs on Polyhexanide
Definitions
Definitions of Polyhexanide
Patient Resources / Community
Patient resources on Polyhexanide Discussion groups on Polyhexanide Patient Handouts on Polyhexanide Directions to Hospitals Treating Polyhexanide Risk calculators and risk factors for Polyhexanide
Healthcare Provider Resources
Symptoms of Polyhexanide Causes & Risk Factors for Polyhexanide Diagnostic studies for Polyhexanide Treatment of Polyhexanide
Continuing Medical Education (CME)
CME Programs on Polyhexanide
International
Polyhexanide en Espanol Polyhexanide en Francais
Business
Polyhexanide in the Marketplace Patents on Polyhexanide
Experimental / Informatics
List of terms related to Polyhexanide

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use it is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, and Omnicide. PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).

Some products containing PHMB are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.

Branded as Baquacil, it also has an application as a swimming-pool and spa water sanitizer in place of chlorine- or bromine-based products.

PHMB is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.

The PHMB hydrochloride salt (solution) is used in the majority of formulations.

See also

• Polyaminopropyl biguanide, a related biguanide disinfectant