Pneumocyte

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The alveoli are lined with two types of cell, the Type I and Type II pneumocytes.

Type I

The Type I pneumocyte is a very large, thin cell stretched over a very large area. This cell cannot replicate and is susceptible to a large number of toxic insults. Type I pneumocytes are responsible for gas exchange occurring in the alveoli.

Type II

Alveolar type II cell, the lamellar bodies can be seen leaving the surface of the cell.

The Type II granular pneumocyte is a roughly cuboidal cell that is usually found at the alveolar septal junctions. Type II cells cover about 5% of the surface area of the alveoli, whereas type I pneumocytes (because of their squamous shape) cover 95% of the total area. Even though they cover less surface area, type II cells greatly outnumber type I cells. Type II cells are responsible for the production and secretion of surfactant.

The Type II pneumocyte can replicate in the alveoli and will replicate to replace damaged Type I pneumocytes.

Type II pneumocytes are larger than type I pneumocytes.

See also

• Alveolar-capillary barrier
• Dust cell

External links

• p_25/12650572 at Dorland's Medical Dictionary
• Histology at KUMC resp-resp17 - "Alveoli"
• Histology at Boston University 13905loa
• Electron micrograph at luc.edu
• Electron micrographs at buffalo.edu

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| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Pneumocyte | list6 = US National Guidelines Clearinghouse on Pneumocyte • NICE Guidance on Pneumocyte • NHS PRODIGY Guidance • FDA on Pneumocyte • CDC on Pneumocyte

| group7 = Textbook Information on Pneumocyte | list7 = Books and Textbook Information on Pneumocyte

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| group9 = Genetics, Pharmacogenomics, and Proteinomics of Pneumocyte | list9 = AND (pharmacogenomics)}} Genetics of Pneumocyte • AND (pharmacogenomics)}} Pharmacogenomics of Pneumocyte • AND (proteomics)}} Proteomics of Pneumocyte

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| group16 = Business Resources on Pneumocyte | list16 = Pneumocyte in the Marketplace • Patents on Pneumocyte

| group17 = Informatics Resources on Pneumocyte | list17 = List of terms related to Pneumocyte

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