Placental abruption overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun M.D., PhD. Rana aljebzi, M.D.[2]

Overview

Placental abruption is a complication of pregnancy, where the placental lining has separated from the uterus of the mother after 20 weeks of gestation and prior to second stage of labor.Placental abruption is a relatively rare but serious complication of pregnancy and placed the well-being of both mother and fetus at risk.[1]

Epidemiology and Demographics

It occurs in 1% of pregnancies world wide with a fetal mortality rate of 20-40% depending on the degree of separation. Placental abruption is also a significant contributor to maternal mortality. The heart rate of the fetus can be associated with the severity.[2]

References

  1. Workalemahu T, Enquobahrie DA, Gelaye B, Thornton TA, Tekola-Ayele F, Sanchez SE; et al. (2018). "Abruptio placentae risk and genetic variations in mitochondrial biogenesis and oxidative phosphorylation: replication of a candidate gene association study". Am J Obstet Gynecol. 219 (6): 617.e1–617.e17. doi:10.1016/j.ajog.2018.08.042. PMC 6497388. PMID 30194050.
  2. Usui R, Matsubara S, Ohkuchi A; et al. (2007). "Fetal heart rate pattern reflecting the severity of placental abruption". doi:10.1007/s00404-007-0471-9. PMID 17896112.

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