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Philtrum highlighted in sunlight
Precursor medial nasal prominence[1]
Dorlands/Elsevier p_17/12635445

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The philtrum (Greek philtron, from philein, "to love; to kiss"), also known as the infranasal depression, is the vertical groove in the upper lip, formed where the nasomedial and maxillary processes meet during embryonic development.

The philtrum allows humans to express a much larger range of lip motions than would otherwise be possible, which enhances vocal and non-verbal communication.


When these processes fail to fuse fully, a cleft lip (sometimes called a "hare lip") can result.

A flattened or smooth philtrum can be a symptom of Fetal alcohol syndrome.[2]


The ancient Greeks used to believe that the philtrum was one of the most erogenous spots on the human body, hence the etymology.[3]


According to the Jewish Talmud (Niddah 30b), God sends an angel to each womb and teaches a baby all the wisdom that can be obtained. Just before the unborn baby comes out, the angel touches it between the upper lip and the nose and all that it has taught the baby is forgotten.

Commentries on this particular story can be found in "What the Angel Taught you" by Rabbi Noah Weinberg and Yaakov Salomon (ISBN 1-57819-134-3).

Similarly, in other folksayings, it is said that an angel "shushes" the baby in the womb, to stop it from talking about heaven, or to forget. Other stories say that it is an indent left by the finger of God. Still more say that it is the spot where the angel put his finger to "shush" the child after having told it a secret. (This was memorably referenced in the film The Prophecy by the arch-angel Gabriel (Christopher Walken).)

See also


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| group5 = Clinical Trials Involving Philtrum | list5 = Ongoing Trials on Philtrum at Clinical Trials.govTrial results on PhiltrumClinical Trials on Philtrum at Google

| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Philtrum | list6 = US National Guidelines Clearinghouse on PhiltrumNICE Guidance on PhiltrumNHS PRODIGY GuidanceFDA on PhiltrumCDC on Philtrum

| group7 = Textbook Information on Philtrum | list7 = Books and Textbook Information on Philtrum

| group8 = Pharmacology Resources on Philtrum | list8 = AND (Dose)}} Dosing of PhiltrumAND (drug interactions)}} Drug interactions with PhiltrumAND (side effects)}} Side effects of PhiltrumAND (Allergy)}} Allergic reactions to PhiltrumAND (overdose)}} Overdose information on PhiltrumAND (carcinogenicity)}} Carcinogenicity information on PhiltrumAND (pregnancy)}} Philtrum in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Philtrum

| group9 = Genetics, Pharmacogenomics, and Proteinomics of Philtrum | list9 = AND (pharmacogenomics)}} Genetics of PhiltrumAND (pharmacogenomics)}} Pharmacogenomics of PhiltrumAND (proteomics)}} Proteomics of Philtrum

| group10 = Newstories on Philtrum | list10 = Philtrum in the newsBe alerted to news on PhiltrumNews trends on Philtrum

| group11 = Commentary on Philtrum | list11 = Blogs on Philtrum

| group12 = Patient Resources on Philtrum | list12 = Patient resources on PhiltrumDiscussion groups on PhiltrumPatient Handouts on PhiltrumDirections to Hospitals Treating PhiltrumRisk calculators and risk factors for Philtrum

| group13 = Healthcare Provider Resources on Philtrum | list13 = Symptoms of PhiltrumCauses & Risk Factors for PhiltrumDiagnostic studies for PhiltrumTreatment of Philtrum

| group14 = Continuing Medical Education (CME) Programs on Philtrum | list14 = CME Programs on Philtrum

| group15 = International Resources on Philtrum | list15 = Philtrum en EspanolPhiltrum en Francais

| group16 = Business Resources on Philtrum | list16 = Philtrum in the MarketplacePatents on Philtrum

| group17 = Informatics Resources on Philtrum | list17 = List of terms related to Philtrum