Peripheral neuropathy MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
MRI is not commonly used in diagnosis and evaluation of peripheral neuropathy but it may be helpful in the diagnosis of some kinds of peripheral neuropathy and other associated soft tissue damages. Normal nerves appear isointense to the surrounding tissue on T1- and T2-weighted (w) MRIs, but upon injury the nerves become hyperintense and thus visible on T2-w MRI. In certain instances, MRI may confer additional diagnostic advantages in peripheral neuropathy such as improved tissue characterization and imaging of deep or bone-encased structures. Interpretation of MRI of peripheral nerves requires availability of clinical differential diagnoses and experience in performing studies. MRI may have some advantages in comparison to other non-invasive imaging methods of peripheral nerves imagings such as: Can be used to develop numerical nerve health standards for clinical applications, correlates with electrophysiology, correlates with axon count and myelination, has a high sensitivity and specificity, determines stage of nerve injury, MRI cannot examine long nerves in a single scan and cannot determine degree of nerve injury.
MRI
- MRI is not commonly used in diagnosis and evaluation of peripheral neuropathy but it may be helpful in the diagnosis of some kinds of peripheral neuropathy and other associated soft tissue damages.[1][2]
- Normal nerves appear isointense to the surrounding tissue on T1- and T2-weighted (w) MRIs, but upon injury the nerves become hyperintense and thus visible on T2-w MRI. [1]
- In certain instances, MRI may confer additional diagnostic advantages in peripheral neuropathy such as improved tissue characterization and imaging of deep or bone-encased structures.[3]
- Interpretation of MRI of peripheral nerves requires availability of clinical differential diagnoses and experience in performing studies.[3]
- MRI may have some advantages in comparison to other non-invasive imaging methods of peripheral nerves imagings such as:[4]
- Can be used to develop numerical nerve health standards for clinical applications
- Correlates with electrophysiology
- Correlates with axon count and myelination
- Has a high sensitivity and specificity
- Determines stage of nerve injury
References
- ↑ 1.0 1.1 Noskin GA, Kalish SB (1991). "Pott's puffy tumor: a complication of intranasal cocaine abuse". Rev Infect Dis. 13 (4): 606–8. PMID 1925277.
- ↑ Low KT, Peh WC (2015). "Magnetic resonance imaging of diabetic foot complications". Singapore Med J. 56 (1): 23–33, quiz 34. PMC 4325563. PMID 25640096.
- ↑ 3.0 3.1 Zaidman CM, Seelig MJ, Baker JC, Mackinnon SE, Pestronk A (2013). "Detection of peripheral nerve pathology: comparison of ultrasound and MRI". Neurology. 80 (18): 1634–40. doi:10.1212/WNL.0b013e3182904f3f. PMC 4214100. PMID 23553474.
- ↑ 4.0 4.1 Rangavajla G, Mokarram N, Masoodzadehgan N, Pai SB, Bellamkonda RV (2014). "Noninvasive imaging of peripheral nerves". Cells Tissues Organs. 200 (1): 69–77. doi:10.1159/000369451. PMC 4494672. PMID 25766202.