Papillary muscle rupture
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| Papillary muscle rupture Classification and external resources | |
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| Papillary Muscle Infarct with Rupture: Gross, an excellent example of ruptured papillary muscle. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology |
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Overview
Papillary muscle rupture is an infrequent mechanical complication of acute myocardial infarction. Early diagnosis is important so that surgical repair can be performed.
Pathophysiology
The vascularization of the papillary muscles shows many individual variations and depends in part on coronary artery anatomy and dominance. However, the posterior papillary muscle is vascularized by posterior left ventricular branches that may have origin in the right, left or both coronary arteries. The anterior papillary muscle is vascularized by branches from diagonal, circumflex or even acute marginal branches of the left coronary artery. Papillary muscle ischemia occurs along with ischemia of the adjacent ventricular wall.
Pathological Findings
Images shown below are courtesy of Professor Peter Anderson DVM PhD and published with permission. © PEIR, University of Alabama at Birmingham, Department of Pathology
 Papillary Muscle Infarct with Rupture: Gross, left ventricle opened partially to show infarct and ruptured muscle, an excellent example |
 Papillary Muscle Infarct with Rupture: Gross, very good example |
 Papillary Muscle Infarct: Gross, an excellent example |
 Papillary Muscle Infarct: Gross, an excellent example |
 Papillary Muscle Infarct with Rupture: Gross, horizontal section of left ventricle looking toward base of heart, a very good example with lateral wall transmural infarct and ruptured papillary muscle |
Papillary Muscle Infarct with Rupture: Gross, an excellent example of ruptured papillary muscle |
 Papillary Muscle Infarct with Rupture |
 Papillary Muscle Infarct with Rupture: Gross, natural color, close-up, well shown |
 Papillary Muscle Infarct: Gross fixed tissue very well shown and typical papillary muscle infarct |
 Papillary Muscle Infarct: Gross, natural color, close-up view of longitudinally section. Papillary muscle with obvious infarct, a very good example. There is a large old infarct with aneurysm in the anterior wall. The infarcted papillary muscle is the posterior one. |
 Papillary Muscle Thinning: Gross, natural color, band-like anterior papillary muscles secondary to healed infarct which is present in picture (but not easily seen). An excellent example for papillary muscle change |
 Mitral Valve Prosthesis and Large Apical Infarct: Gross, natural color, caged plastic ball with complete steel struts. A large recent infarct at apex of heart, at base of posterior papillary muscles. Etiology not completely clear but looks like an iatrogenic lesion (good illustration) |
 Myocardial Hemorrhage Following Mitral Valve Replacement: Gross, natural color, horizontal section of left ventricle showing a large area of mural hemorrhage extending from anterior papillary muscle |
 Papillary Muscle Infarct with Rupture: Gross, natural color, a close-up view (very good example) |
 Papillary Muscle Infarct with Rupture: Gross, fixed tissue, a close-up view (quite good example) |
 Papillary Muscle Infarct with Rupture: Gross, fixed tissue, but good color. Horizontal slice of LV with posterior infarct that appears old and a ruptured papillary muscle head. |
 Papillary Muscle Infarct with Rupture: Gross, fixed tissue, but good color. An outstanding photo of ruptured head of posterior papillary muscle with entangled chordae |
 Papillary Muscle Infarct with Rupture: Gross, fixed tissue, but good color. An outstanding photo of ruptured head of posterior papillary muscle with entwined chordae |
 Papillary Muscle Infarct with Rupture: Gross, fixed tissue, but good color. An outstanding photo of ruptured head of posterior papillary muscle with entwined chordae |
Video: Ruptured papillary muscle and severe MR
References
- Kyo S, Miyamoto N, Yokote Y, et al. [Papillary muscle rupture complicating acute myocardial infarction--treatment with mitral valve replacement and coronary bypass surgery in acute phase] Nippon Kyobu Geka Gakkai Zasshi 1996 Jun; 44(6):874-81.
- Tavakoli R, Weber A, Vogt P, et al. Surgical management of acute mitral valve regurgitation due to post-infarction papillary muscle rupture. J Heart Valve Dis 2002 Jan; 11(1):20-5; discussion 26.
- Nunley DL, Starr A Papillary muscle rupture complicating acute myocardial infarction. Treatment with mitral valve replacement and coronary bypass surgery. Am J Surg 1983 May; 145(5):574-7.
- Goh K, Kubo Y, Sasajima T, et al. [Emergency CABG and mitral valve replacement for anterolateral papillary muscle rupture after acute myocardial infarction] Nippon Kyobu Geka Gakkai Zasshi 1995 Jul; 43(7):1034-8.
- Yanagi H, Kondo J, Uchida K, et al. [A case of emergency surgery for acute mitral regurgitation due to complete papillary muscle rupture as complication of acute inferior myocardial infarction] Jpn J Thorac Cardiovasc Surg 1998 Oct; 46(10):1014-9.
- Sasaki Y, Suehiro S, Shibata T, et al. [Mitral valve replacement and coronary artery bypass grafting for postinfarction mitral papillary muscle rupture] Nippon Kyobu Geka Gakkai Zasshi 1996 May; 44(5):697-701.
- Minakata K, Konishi Y, Matsumoto M, et al. [A case of scheduled mitral valve replacement for mitral regurgitation caused by papillary muscle rupture after acute myocardial infarction] Nippon Kyobu Geka Gakkai Zasshi 1997 Apr; 45(4):639-44.
- Tepe NA, Edmunds LH Operation for acute postinfarction mitral insufficiency and cardiogenic shock. J Thorac Cardiovasc Surg 1985 Apr; 89(4):525-30.
- Ueno Y, Toba T, Ezaki H, et al. [Mitral valve replacement with concomitant coronary bypass for the papillary muscle rupture after acute myocardial infarction in situs inversus] Kyobu Geka 1992 Oct; 45(11):1031-4.
- Minami H, Mukohara N, Obo H, et al. Papillary muscle rupture following acute myocardial infarction. Jpn J Thorac Cardiovasc Surg 2004 Aug; 52(8):367-71.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
