Otitis media historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Acute otitis media was first described by Hippocrates in the 5th century B.C.E. The first recorded surgical incision for treatment of medial ear infection was in the 16th century C.E., performed by French physician Ambroise Paré. Initial therapies for otitis media were surgical, particularly mastoidectomy, which was first performed by French physician Jean-Louis Petit in the 17th century C.E. German physicians Hermann Schwartze, Anton von Troltsch, and Adam Politzer published the first journal dedicated to ear pathology and treatment in 1865. Antibiotic therapy for otitis media treatment emerged with the invention of mass production of penicillin in 1940 by Alexander Fleming, Howard Florey, and Ernst Chain. The pneumococcal conjugate vaccine (PCV) emerged in 2000, greatly reducing the incidence of otitis media by vaccinating individuals against the causative pathogens.[1][2]

Discovery

  • Mastoiditis was first described by Hippocrates in the 5th century B.C.E.[3]

Landmark Events in the Development of Treatment Strategies

  • The first recorded surgical incision for treatment of medial ear infection was in the 16th century C.E., performed by French physician Ambroise Paré.[4]
  • Initial therapies for otitis media were surgical, particularly mastoidectomy, which was first performed by French physician Jean-Louis Petit in the 17th century C.E.[4]
    • The procedure was first used for the purpose of draining pus from an abscess.[4]
  • German physicians Hermann Schwartze, Anton von Troltsch, and Adam Politzer advanced the discourse of clinicial study of otitis media by publishing the first journal dedicated to ear pathology and treatment in 1865.[4]
  • Adam Politzer founded the first otology clinic in 1873 in Austria, beginning the codification and standardization of ear disease treatment, such as otitis media.
  • Antibiotic therapy for otitis media treatment emerged with the invention of mass production of penicillin in 1940 by Alexander Fleming, Howard Florey, and Ernst Chain.[5]
    • This was the first instance of the modern use of antibiotic therapy, as opposed to surgery, for otitis media treatment.
  • The pneumococcal conjugate vaccine (PCV) emerged in 2000, greatly reducing the incidence of otitis media by vaccinating individuals against the causative pathogens.[1]

References

  1. 1.0 1.1 Marom T, Tan A, Wilkinson GS, Pierson KS, Freeman JL, Chonmaitree T (2014). "Trends in otitis media-related health care use in the United States, 2001-2011". JAMA Pediatr. 168 (1): 68–75. doi:10.1001/jamapediatrics.2013.3924. PMC 3947317. PMID 24276262.
  2. Titche LL, Wachter RD, Coulthard SW, Harries LL (1981). "Mastoiditis in prehistoric Arizona Indians". Ariz Med. 38 (9): 712–4. PMID 7028002.
  3. Modak VB, Chavan VR, Borade VR, Kotnis DP, Jaiswal SJ (2005). "Intracranial complications of otitis media: In retrospect". Indian J Otolaryngol Head Neck Surg. 57 (2): 130–5. doi:10.1007/BF02907667. PMC 3450981. PMID 23120149.
  4. 4.0 4.1 4.2 4.3 Bento RF, Fonseca AC (2013). "A brief history of mastoidectomy". Int Arch Otorhinolaryngol. 17 (2): 168–78. doi:10.7162/S1809-97772013000200009. PMC 4423283. PMID 25992009.
  5. Diamant H, Hultcrantz M (1996). "[Glimpses from the history of otitis media]". Nord Medicinhist Arsb (in Swedish): 189–95. PMID 11624973.

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