Osteomyelitis classification

Jump to navigation Jump to search

Osteomyelitis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Osteomyelitis from Other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications, and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Osteomyelitis classification On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Osteomyelitis classification

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Osteomyelitis classification

CDC on Osteomyelitis classification

Osteomyelitis classification in the news

Blogs on Osteomyelitis classification

Directions to Hospitals Treating Osteomyelitis

Risk calculators and risk factors for Osteomyelitis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A., Seyedmahdi Pahlavani, M.D. [2]

Overview

There are many classification systems for osteomyelitis. In general, there are three major classification systems which include; classification according to the symptom chronology, Lew and Waldvogel classification, and Cierny and Mader classification. Osteomyelitis may be classified according to the symptom chronology into acute, sub-acute (further subdivided into the Glendhill and Robert et al. systems), and chronic. Chronic osteomyelitis may be subdivided into Lew and Waldvogel's classification system and Cierny and Mader's classification system. Osteomyelitis may be classified according to Lew and Waldvogel's system based on the duration and mechanism of infection into 3 subtypes which are; hematogenouos osteomyelitis, contiguous-focus osteomyelitis, and osteomyeltis secondary to vascular insufficiency. Osteomyelitis may be classified according to Cierny and Mader's classification system based on the anatomy of bone infection (4 stages) and host physiology (3 levels of compromise).

Classification

There are many classification systems for osteomyelitis:

  • Osteomyelitis may be classified according to symptom chronology into acute, sub-acute (further subdivided into the Glendhill and Robert et al. systems), and chronic
  • Lew and Waldvogel classified osteomyelitis according to the duration and mechanism of infection (traditional classification)[1]
  • Cierny and Mader classified osteomyelitis according to the anatomy of bone infection and host physiology[2]
  • The Cierny and Mader system offers a guide to treatment

Classification based on symptom chronology

  • Acute osteomyelitis: Osteomyelitis is classified as acute if the duration of the disease has been less than 2 weeks.
  • Sub-acute: Sub-acute hematogenous osteomyelitis has a more insidious onset and lacks the severity of symptoms, which makes the diagnosis of this disorder difficult. Typically, diagnosis is delayed for more than 2 weeks.
Sub-acute osteomyelitis
TYPE GLEDHILL CLASSIFICATION ROBERT ET AL. CLASSIFICATION
I Solitary localized zone of radiolucency surrounded
by reactive new bone formation
Ia—Punched-out radiolucency
Ib—Punched-out radiolucent lesion with sclerotic margin
II Metaphyseal radiolucencies with cortical erosion --
III Cortical hyperostosis in diaphysis; no onion skin reaction Localized cortical periosteal reaction
IV Subperiosteal new bone and onion skin layering Onion skin periosteal reaction
V -- Central radiolucency in epiphysis
VI -- Destructive process involving vertebral body


  • Chronic Ostemyelitis: Chronic osteomyelitis is defined as persistent pain, erythema, or swelling, sometimes in association with a draining sinus tract that mostly lasts for more than 4 weeks.

The following table describes the classification schemes for chronic osteomyelitis.

Lew and Waldvogel Etiologic System

Mechanism of Infection Description
Hematogenous Osteomyelitis Osteomyelitis develops after bacteremia
Contiguous-focus Osteomyelitis Direct inoculation of bone via trauma/fracture, surgery, prosthetic devices, or spread from soft tissue
Osteomyelitis Secondary to Vascular Insufficiency Reduced blood supply, usually in diabetic patients

Cierny and Mader Staging System

Classification Description
Anotomic Type Stage 1 Medullary osteomyeltitis: infection confined to the intramedullary bone surfaces
Stage 2 Superficial osteomyelitis: true contiguous infection (bone surface undergoes necrosis at the base of a soft tissue wound)
Stage 3 Localized osteomyelitis: full-thickness, cortical sequestration
Stage 4 Diffuse osteomyelitis: through-and-through process requiring intercalary reconstruction of bone
Physiological Class A Host Normal physiological, metabolic, and immunologic states
B Host Local compromise, systemic compromise, or both
C Host Morbidity of treatment is worse than disease

References

  1. Lew, Daniel P.; Waldvogel, Francis A. (1997). "Osteomyelitis". New England Journal of Medicine. 336 (14): 999–1007. doi:10.1056/NEJM199704033361406. ISSN 0028-4793.
  2. Mader, Jon T.; Shirtliff, Mark; Calhoun, Jason H. (1997). "Staging and Staging Application in Osteomyelitis". Clinical Infectious Diseases. 25 (6): 1303–1309. doi:10.1086/516149. ISSN 1058-4838.