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In an analysis of data from the Get With the Guidelines - Coronary Artery Disease (GWTG- CAD) registry, researchers investigated gender differences in methods of care and in-hospital deaths based on 78,425 acute myocardial infarction (AMI) patients in 420 US hospitals between 2001 to 2006. After multivariable adjustment, there were no significant differences found for in-hospital mortality between men and women overall; however, in an analysis of the STEMI subpopulation, researchers reported that women had a 12% greater risk of in-hospital mortality (p=0.015). Additional differences were found in issues of medical care. Females were less likely to be treated within 24 hours with aspirin (adjusted odds ratio: 0.86, p <0.0001) or beta-blockers (adjusted odds ratio: 0.90, p <0.0001), were less likely to receive reperfusion therapy within 30 minutes of arriving at the hospital (adjusted odds ratio: 0.78, p=0.004) and were less likely to undergo catheterization after their MI (adjusted odds ratio: 0.91, p<0.0001). These differences in guidelines-based treatment and outcomes reveal "the existing opportunities to improve the provision of healthcare among women hospitalized with AMI." (Circulation by Hani Jneid et al.)
