Neutralisation (immunology)

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Assistant Editor-in-Chief: Soumya Sachdeva

Neutralisation (or neutralization) in the immunological sense refers to the ability of antibodies to block the site(s) on bacteria or viruses that they use to enter their target cell.

An antibody produced in response to a bacterial exotoxin or a toxoid that neutralizes the exotoxin is called an antitoxin

In neutralization reactions, the harmful effects of a bacterial exotoxin or virus are eliminated by a specific antibody.

In a virus neutralization test, the presence of antibodies against a virus can be detected by the antibodies’ ability to prevent cytopathic effects of viruses in cell cultures.

Antibodies against certain viruses can be detected by their ability to interfere with viral hemagglutination in viral hemagglutination inhibition tests.


neutralisation is an act or aprocess of neutralising.


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