Nasopharyngeal carcinoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]Faizan Sheraz, M.D. [3]

Overview

World health organization classified nasopharyngeal carcinoma into 3 types : keratinizing, nonkeratinizing (differentiated, undifferentiated) and basaloid squamous cell carcinoma.

Classification

World Health Organization (WHO) classification (2005) for nasopharyngeal carcinoma (NPC):[1][2]

Classification Former name EBV Prevalence Prognosis
Keratinizing Type 1, squamous cell carcinoma -ve almost 1/4 of NPC cases poor
Nonkeratinizing, differentiated Type 2, transitional carcinoma +ve less than 1/6 of NPC cases good
Nonkeratinizing, undifferentiated Type 3, lymphoepithelial carcinoma +ve most common good
Basaloid squamous cell carcinoma (BSCC) least common poor

References

  1. Barnes, Leon (2005). Pathology and genetics of head and neck tumours. Lyon: IARC Press. ISBN 978-92-832-2417-4.
  2. Thompson, Lester (2011). Diagnostic pathology. Salt Lake City, Utah: Amirsys. ISBN 1931884617.

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