NUP107

Nucleoporin 107kDa
Identifiers
Symbols	NUP107 ; NUP84
External IDs	Template:OMIM5 Template:MGI HomoloGene: 5555
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE NUP107 218768 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Nucleoporin 107kDa, also known as NUP107, is a human gene.

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Further reading

• Bastos R, Ribas de Pouplana L, Enarson M; et al. (1997). "Nup84, a novel nucleoporin that is associated with CAN/Nup214 on the cytoplasmic face of the nuclear pore complex". J. Cell Biol. 137 (5): 989–1000. PMID 9166401.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Belgareh N, Rabut G, Baï SW; et al. (2001). "An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells". J. Cell Biol. 154 (6): 1147–60. doi:10.1083/jcb.200101081. PMID 11564755.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vasu S, Shah S, Orjalo A; et al. (2001). "Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export". J. Cell Biol. 155 (3): 339–54. doi:10.1083/jcb.200108007. PMID 11684705.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Boehmer T, Enninga J, Dales S; et al. (2003). "Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex". Proc. Natl. Acad. Sci. U.S.A. 100 (3): 981–5. doi:10.1073/pnas.252749899. PMID 12552102.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Walther TC, Alves A, Pickersgill H; et al. (2003). "The conserved Nup107-160 complex is critical for nuclear pore complex assembly". Cell. 113 (2): 195–206. PMID 12705868.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Walther TC, Askjaer P, Gentzel M; et al. (2003). "RanGTP mediates nuclear pore complex assembly". Nature. 424 (6949): 689–94. doi:10.1038/nature01898. PMID 12894213.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Loïodice I, Alves A, Rabut G; et al. (2005). "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Mol. Biol. Cell. 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878. PMID 15146057.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Krull S, Thyberg J, Björkroth B; et al. (2005). "Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket". Mol. Biol. Cell. 15 (9): 4261–77. doi:10.1091/mbc.E04-03-0165. PMID 15229283.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Berke IC, Boehmer T, Blobel G, Schwartz TU (2005). "Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex". J. Cell Biol. 167 (4): 591–7. doi:10.1083/jcb.200408109. PMID 15557116.CS1 maint: Multiple names: authors list (link)
• Nousiainen M, Silljé HH, Sauer G; et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Orjalo AV, Arnaoutov A, Shen Z; et al. (2006). "The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly". Mol. Biol. Cell. 17 (9): 3806–18. doi:10.1091/mbc.E05-11-1061. PMID 16807356.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glavy JS, Krutchinsky AN, Cristea IM; et al. (2007). "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 3811–6. doi:10.1073/pnas.0700058104. PMID 17360435.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zuccolo M, Alves A, Galy V; et al. (2007). "The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions". EMBO J. 26 (7): 1853–64. doi:10.1038/sj.emboj.7601642. PMID 17363900.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Boehmer T, Schwartz TU (2007). "Purification, crystallization and preliminary X-ray analysis of a Nup107-Nup133 heterodimeric nucleoporin complex". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63 (Pt 9): 816–8. doi:10.1107/S1744309107040523. PMID 17768364.